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Search Publications by Anthony J. Kearsley

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Displaying 1 - 25 of 57

Diffusion-limited reactions in nanoscale electronics

Author(s)
Ryan M. Evans, Arvind K. Balijepalli, Anthony J. Kearsley
To quantify interactions between drug molecules and target receptors, a novel nanoscale electronics instrument is under development. The instrument consists of

Revealing thermodynamics of DNA origami folding via affine transformations

Author(s)
Jacob M. Majikes, Paul N. Patrone, Daniel R. Schiffels, Michael P. Zwolak, Anthony J. Kearsley, Samuel P. Forry, James A. Liddle
Structural DNA nanotechnology, as exemplified by DNA origami, has enabled the design and construction of molecularly precise objects for a myriad of

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics

Author(s)
Robert G. Brinson, John P. Marino, Frank Delaglio, Luke W. Arbogast, Ryan M. Evans, Anthony J. Kearsley, Yves Aubin, Gregory Pierens, Xinying Jia, David Keizer, Jonas Stahle, Goran Widmalm, Chad Lawrence, Patrick Reardon, John Cort, Koichi Kato, Stuart Parnham, Andreas Blomgren, Torgny Rundlof, Kang Chen, David Keire, Thea Suter-Stahel, Gerhard Wider, Donna Baldisseri, Julie Wu, Mats Wikstrom, Medhi Mobli
Of the top ten drugs on the global market in 2016, seven of them are biologics with a combined market value of over US$60 billion. Moreover, around 2,800

Stochastic Regression Modeling of Chemical Spectra

Author(s)
Anthony J. Kearsley, William E. Wallace, Yutheeka Gadhyan
A stochastic regression method has been developed that decomposes chemical spectra into separate contributions from signal and from noise. The numerical results