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Search Publications

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Displaying 1226 - 1250 of 143606

Exploiting the Digital Economy for Product Realization in Manufacturing

April 1, 2024
Author(s)
Paul Witherell, Soundar Kumara
In this paper we briefly discuss the evolving concepts of digital economy, digital threads, and product realization (manufacturing) in the digital economy enabled futuristic world. We posit that if we need to become self-sufficient, it is imperative that

Mechanism of Action, Potency and Efficacy: Considerations for Cell and Gene Therapies

April 1, 2024
Author(s)
Carl Simon Jr., Anne L. Plant, Catherine Zander, Erich Bozenhardt, Christina Celluzzi, David Dobnik, Melanie Grant, John Hughes, Uma Lakshmipathy, Kok-Seong Lim, Laura Montgomery, Hesham Nawar, Thiana Nebel, Linda Peltier, James Sherley, Rouzbeh Taghizadeh, Eddie Tan, Sandrine Vessillier
One of the most challenging aspects of cell and gene therapy products (CGTPs) is defining mechanism of action (MOA), potency and efficacy of the product. This perspective examines these concepts and presents helpful ways to think about them through the

Quantitative and Standardized Pseudovirus Neutralization Assay for COVID-19

April 1, 2024
Author(s)
Jerilyn Izac, Edward Kwee, Adolfas Gaigalas, Lili Wang
COVID-19 is a global pandemic caused by the highly infectious SARS-CoV-2 virus. Efforts to combat SARS-CoV-2 infection include mass vaccination and development of monoclonal and convalescent plasma therapeutics that require precise measurements of

Sampling of Microplastics at a Municipal Recycling Facility

April 1, 2024
Author(s)
Abigail P. Lindstrom, Joseph M. Conny, Diana Ortiz-Montalvo
Particulate sampling was carried out at a local municipal recycling facility near a conveyer belt containing sorted plastic materials to collect airborne environmental particles on filters. Nucleopore filters were mounted on Teflon support rings, coated

Simulation of Neutron Dark-Field Data for Grating-Based Interferometers

April 1, 2024
Author(s)
Caitlyn Wolf, Youngju Kim, Paul A. Kienzle, Pushkar Sathe, Michael Daugherty, Peter Bajcsy, Daniel Hussey, Kathleen Weigandt
Hierarchical structures and heterogeneous materials are found in many natural and engineered systems including additive manufacturing, alternative energy, biology and polymer science. Though the structure–function relationship is important for developing

The Impact of Outdoor Air Ventilation in School Corridors

April 1, 2024
Author(s)
Lisa Ng, Diane Mills
There were about 55.4 million students enrolled in U.S. elementary and secondary schools in 2021 [1]. Worldwide, there were about 614 million secondary students and 739 million primary students [2], representing over 17 % of our global population [3]. In

ALF

March 31, 2024
Author(s)
Hayden Evans, Taner N. Yildirim, Peng Peng, Yongqiang Cheng, Zeyu Deng, Qiang Zhang, Dinesh Mullangi, Dan Zhao, Pieremanuele Canepa, Hanna Breunig, Anthony Cheetham, Craig Brown

Cyclostationary Channel Power Measurements for CBRS Coexistence Assessment

March 31, 2024
Author(s)
Dan Kuester, Anthony Romaniello, PETER MATHYS
We present a compressive approach for channel power measurements in coexistence scenarios involving heterogeneous cyclostationary channel usage and an example application in the Citizens Broadband Radio Service (CBRS) band. The method leverages known cycle

Programmable electrical coupling between stochastic magnetic tunnel junctions

March 29, 2024
Author(s)
Sidra Gibeault, Temitayo Adeyeye, Liam Pocher, Daniel Lathrop, Matthew Daniels, Mark Stiles, Jabez J. McClelland, William Borders, Jason Ryan, Philippe Talatchian, Ursula Ebels, Advait Madhavan
Superparamagnetic tunnel junctions (SMTJs) are promising sources of randomness for compact and energy efficient implementations of various probabilistic computing techniques. When augmented with electronic circuits, the random telegraph fluctuations of the

Tunable X-band opto-electronic synthesizer with ultralow phase noise

March 29, 2024
Author(s)
Igor Kudelin, Pedram Shirmohammadi, William Groman, Samin Hanifi, Megan Kelleher, Dahyeon Lee, Takuma Nakamura, Charles McLemore, Steven Bowers, Franklyn Quinlan, Scott Diddams
Microwave signals with low phase noise in the X-band (8-12 GHz) are essential for widespread technologies and important scientific developments. Photonic techniques, such as optical frequency division (OFD), leverage the high spectral purity of low-noise

Unbiased random bitstream generation using injection-locked spin-torque nano-oscillators

March 29, 2024
Author(s)
Nhat-Tan PHAN, Nitin Prasad, Abderrazak Hakam, Ahmed SIDI EL VALLI, Lorena Anghel, Luana Carina Benetti, Advait Madhavan, Alex Jenkins, Ricardo Ferreira, Mark Stiles, Ursula Ebels, Philippe Talatchian
Unbiased sources of true randomness are critical for the successful deployment of stochastic unconventional computing schemes and encryption applications in hardware. Leveraging nanoscale thermal magnetization fluctuations provides an efficient and almost

Accelerating Defect Predictions in Semiconductors Using Graph Neural Networks

March 27, 2024
Author(s)
Md. Habibur Rahman, Prince Gollapalli, Panayotis Manganaris, Satyesh Kumar Yadav, Ghanshyam Pilania, Arun Kumar Mannodi-Kanakkithodi, Brian DeCost, Kamal Choudhary
First principles computations reliably predict the energetics of point defects in semiconductors, but are constrained by the expense of using large supercells and advanced levels of theory. Machine learning models trained on computational data, especially

Comparison of a 1 nF Capacitor with a 1 kO Resistor Using a Digital Impedance Bridge

March 27, 2024
Author(s)
Yicheng Wang, Stephan Schlamminger, Dean G. Jarrett, Alireza Panna, Andrew D. Koffman
This paper reports our effort to improve a digital impedance bridge. The limit of the bridge resolution and stability is less than 3 parts in 10^9 for the nominal 1:1 impedance comparison of two 100 pF capacitors. The type-A uncertainty for comparison of a

The Quantum Electro-Mechanical Metrology Suite

March 27, 2024
Author(s)
Frank Seifert, Lorenz Keck, David B. Newell, Darine El Haddad
The National Institute of Standards and Technology (NIST) is building a robust open-source hardware and software Quantum Electro-Mechanical Metrology Suite (QEMMS) that can provide quantum voltage, resistance, current, mass, and force dissemination

Workshop on Quantifying Methane Emissions Across Natural Gas Infrastructure in Urban Environments

March 27, 2024
Author(s)
Anna Karion, Paul Shepson, Thomas Butcher, Roisin Commane, Julianne M Fernandez, Tom Ferrara, Kristian Hajny, Robert Jackson, Brian Lamb, Israel Lopez Coto, Zeyneb Magavi, Brian McDonald, Zachary Merrin, Scot Miller, Kimberly Mueller, Lee Murray, Joseph Pitt, Rick Trieste, Rebecca Trojanowski, Joseph von Fischer
A workshop was held at the EDF offices in Washington, DC, on June 15 and 16, 2022, to discuss the current state of knowledge and to define productive courses of action in better determination and source apportionment of methane emission rates, and

AI Use Taxonomy: A Human-Centered Approach

March 26, 2024
Author(s)
Mary Frances Theofanos, Yee-Yin Choong, Theodore Jensen
As artificial intelligence (AI) systems continue to be developed, humans will increasingly participate in human-AI interactions. Humans interact with AI systems to achieve particular goals. To ensure that AI systems contribute positively to human-AI

Certification Approaches for Weigh-In-Motion Systems in Law Enforcement Applications

March 26, 2024
Author(s)
Katrice Lippa, Jan Konijnenburg, Loren Minnich, Tanvi Pandya, James Willis
Every day, overweight and excessively heavy vehicles cause damage to roads, bridges, and other vehicle-based infrastructure. To protect this vital transportation infrastructure for the U.S., states have imposed weight limits for commercial and fleet

Pivotal Roles of Triple Screening-Topological, Electrostatic, and Hydrodynamic-On Dynamics in Semidilute Polyelectrolyte Solutions

March 26, 2024
Author(s)
Rajeev Kumar, Ali Slim, Antonio Faraone, Jan-Michael Carrillo, Ryan Poling-Skutvik, Murugappan Muthukumar, Amanda Marciel, Jacinta Conrad
For semidilute polyelectrolyte solutions, it is generally assumed that topological, electrostatic, and hydrodynamic interactions are screened (called triple screening). Despite a large body of research focused on polyelectrolyte solutions, the concept of
Displaying 1226 - 1250 of 143606