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Displaying 651 - 675 of 837

The evaluation of an autosomal SNP 12-plex assay

April 1, 2006
Author(s)
Peter M. Vallone, Amy E. Decker, Michael D. Coble, John M. Butler
SNPs have the potential to play a useful role in human identification testing. Small PCR amplicon sizes associated with SNP typing technologies make SNPs attractive for typing degraded DNA or other low copy number situations. SNP markers can be useful in

Analysis of DNA Single Nucleotide Polymorphisms by Mass Spectrometry

March 17, 2006
Author(s)
Peter Vallone, John Butler
Single nucleotide polymorphisms(SNP) are the most frequent form of DNA sequence variation in the human genome and are becoming increasingly useful as genetic markers for genome mapping studies, medical diagnostics, and human identity testing. The primer

Oxidative Stress and DNA Damage-DNA Repair System in Vascular Smooth Muscle Cells in Artery and Vein Grafts

March 1, 2006
Author(s)
S. H. McLaren, D. Gao, L. Chen, J. R. Eshleman, V. Dawson, M. A. Trush, V. Bohr, M. Dizdaroglu, G. M. Williams, C. Wei
Graft failure in coronary artery bypass grafts (CABGs) utilizing the saphenous vein is significantly higher than in those utilizing the internal mammary artery (IMA) or the radial artery (RA). While a number of studies have described this phenomenon

Standards and Standardization of Molecular Diagnostics

August 15, 2005
Author(s)
J P. Jakupciak, C D. O'Connell
DNA has become a major target for clinical laboratory testing over the past 5 years, and RNA testing is emerging for infectious disease and gene expression (1). To normalize laboratory results across different technology platforms as well as between

Standards for Validation of Cancer Biomarkers

April 2, 2005
Author(s)
Catherine D. O'Connell, Donald H. Atha, J P. Jakupciak
Over the past 10 years, DNA testing to identify disease associated mutations and specific organisms, which represent public health and safety concerns, have become major targets for laboratory testing. RNA testing is also emerging for gene expression, both

Manipulating Cell Adhesion on Gradient Poly(2-Hydroxyethyl Methacrylate)-Grafted Surfaces

April 1, 2005
Author(s)
Ying Mei, Tao Wu, Chang Xu, K J. Langenbach, John T. Elliott, B D. Vogt, Kathryn L. Beers, Eric J. Amis, N Washburn
In this study, a simple and versatile method was developed to prepare the low grafting density initaitor gradient, which was combined with surface initiated atom transfer radical polymerizations (ATRP) to produce a well defined poly(2-hydroxyethyl
Displaying 651 - 675 of 837
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