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Displaying 1 - 5 of 5

Report from the 2023 NIST-Hosted Workshop on Collaborative Efforts to Enable Adoption of Rapid Microbial Testing Methods for Advanced Therapy Products

September 26, 2025
Author(s)
Stephanie Servetas, Dawn Henke, Jason Kralj, Kirsten Parratt, Scott Jackson, Nancy Lin
On April 25, 2023, the National Institute of Standards and Technology (NIST) hosted a one-day hybrid workshop focused on bringing together organizations and working groups with the common goal of enabling validation and implementation of rapid microbial

Characterizing Cell-Free Transcription and Translation Dynamics with Nucleic Acid-Based Assays

August 10, 2025
Author(s)
Fernanda Piorino Macruz de Oliveira, Chad Alan Sundberg, Elizabeth Strychalski, Eugenia Romantseva
Characterization of cell-free expression (CFE) systems must expand beyond single spectrophotometric measurements of a green fluorescent protein to provide meaningful metrics of system performance over the course of a CFE reaction and enable the development

Jointly benchmarking small and structural variant calls with vcfdist

October 2, 2024
Author(s)
Tim Dunn, Justin Zook, James Holt, Satish Narayanasamy
In this work, we extend vcfdist to be the first variant call benchmarking tool to jointly evaluate phased single-nucleotide polymorphisms (SNPs), small insertions/deletions (INDELs), and structural variants (SVs) for the whole genome. First, we find that a

Optimizing Wastewater Surveillance: The Necessity of Standardized Reporting and Proficiency for Public Health

August 7, 2024
Author(s)
Ishi Keenum, Nancy Lin, Alshae Logan, Adam Gushgari, Nishita D'Souza4, Joshua Steele, Devrim Kaya, Lydia Gushgari
Wastewater-based surveillance (WBS) has emerged as a valuable tool for public health, allowing a greater understanding of disease prevalence in communities. With historical significance in monitoring polio transmission,1 WBS gained further prominence in
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