An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Sergey Aganezov, Stephanie Yan, Daniela Soto, Melanie Kirsche, Samantha Zarate, Justin Wagner, Jennifer McDaniel, Nathanael David Olson, Rajiv McCoy, Megan Dennis, Justin Zook, Michael Schatz
Compared to its predecessors, the Telomere-to-Telomere CHM13 genome adds nearly 200 million base pairs of sequence, corrects thousands of structural errors, and unlocks the most complex regions of the human genome for clinical and functional study. We show
Dianne L. Poster, C Cameron Miller, Yaw S. Obeng, John J. Kasianowicz, Michael T. Postek, Norman Horn, Troy Cowan, Richard Martinello
The development of an international, precompetitive, collaborative, ultraviolet (UV) research consortium is discussed as an opportunity to lay the groundwork for a new UV commercial industry and the supply chain to support this industry. History has
Nenad Ivezic, Elena Jelisic, Marija Jankovic, Boonserm Kulvatunyou, Dionysios Kehagias, Zoran Marjanovic
Recently, our interoperability research strategy delivered significant results by (1) adopting the ISO-approved Core Components Technical Specification (CCTS) meta-model as a basis for a new data exchange modeling framework and (2) developing Score, which
Elena Jelisic, Nenad Ivezic, Boonserm Kulvatunyou, Scott Nieman, Zoran Marjanovic
Standards-based methods for data exchange are key for Business-to-Business (B2B) integration. However, in the case of Small Businesses, there are significant barriers to utilizing these methods. One of the reasons is that the standards are large, making
Hugh Hayes, Jerome Mulloor, Michael Nelson, Kate Rimmer, Lee L. Yu, James H. Yen
Standard Reference Material® (SRM®) 3289 Multivitamin Tablets was developed as part of a collaborative effort between the National Institute for Standards and Technology (NIST) and the National Institutes of Health Office of Dietary Supplements (NIH ODS)
Angela Stelson, Aaron Hagerstrom, Jeffrey Jargon, Chris Long
Scattering (S-) parameters are fundamental to numerous microwave quantities including antenna factors, microwave power, and phase. The uncertainty in S-parameter measurements is influenced by the test setup, including instrument noise, drift, position of
Elena Jelisic, Marija Jankovic, Nenad Ivezic, Boonserm Kulvatunyou, Dionysios Kehagias, Zoran Marjanovic
Digital Twins (DTs) are among the most popular and quickly evolving technologies, particularly within Industry 4.0. The rapid expansion of a new generation of information technologies, such as the Internet of Things (IoT), artificial intelligence (AI), and
Marcia L. Huber, Richard A. Perkins, Marc Assael, Stella Monogenidou, Robert Hellmann, Jan Sengers
The International Association for the Properties of Water and Steam (IAPWS) has adopted a new formulation for the thermodynamic properties of heavy water. This manuscript describes the development of a new correlation for the thermal conductivity of heavy
Robert A. Fletcher, James J. Filliben, Nicholas Ritchie
Standard Reference Material (SRM) 2806: Medium Test Dust in Hydraulic Fluid represents a series of reference materials certified by the National Institute of Standards and Technology (NIST) used to calibrate liquid-borne optical (or automatic) particle
Justin Wagner, Nathanael David Olson, Lindsay Harris, Jennifer McDaniel, Fritz Sedlazeck, Chen-Shan Chin, Justin Zook
The repetitive nature and complexity of some medically relevant genes poses a challenge for their accurate analysis in a clinical setting. The Genome in a Bottle Consortium has provided variant benchmark sets, but these exclude nearly 400 medically
This article will discuss quantum impact on the current widely deployed cryptographic mechanisms and introduce approaches being taken by SC27 to prepare for the quantum era.
Benjamin M. Miller, Tom Latourrette, Drake Warren, David Metz
Standards provide critical benefits across a wide variety of contexts, including safety and health, environmental protection, and quality of products and services. However, while these benefits are generally acknowledged, estimating the social and economic
A fundamental equation of state in terms of the Helmholtz energy is presented for vinyl chloride. Due to its fundamental nature, it can be used to consistently calculate all thermodynamic state properties in the fluid region. Based on the underlying
The multi-source common-view disciplined clock (MSCVDC) is a recent NIST invention designed to support critical infrastructure timing systems that require a verifiably accurate and fail-safe clock. This paper introduces the MSCVDC, provides a technical
Alexander Maranghides, Shonali Nazare, Eric Link, Matthew Bundy, Artur A. Chernovsky, Erik L. Johnsson, Kathryn Butler, Steven Hawks, Frank Bigelow, William (Ruddy) Mell, Anthony Bova, Derek McNamara, Tom MIlac, Daniel Gorham, Faraz Hedayati, Bob Raymer, Frank Frievalt, William Walton
The Structure Separation Project is a multi-level project to assess structure-to-structure fire spread in Wildland-Urban Interface (WUI) communities. The project is divided into three phases with each phase assessing radiant and convective heat exposures
NIST Handbook 150-24, NVLAP Law Enforcement and Corrections Equipment, presents the technical requirements and guidance for the accreditation of laboratories that test law enforcement and corrections equipment.
Soonjo Kwon, Laetitia Monnier, Raphael Barbau, William Z. Bernstein
Barbau et al. (2012) propsoed OntoSTEP that enables the translation ofthe STandard for the Exchange of Product Model Data (STEP) schema andits instances to an ontology and a set of knowledge graphs represented in theWeb Ontology Language (OWL). OntoSTEP
Automatic, Automated, or Autonomous - Unmanned Ground Vehicles (A-UGVs), as referred to by ASTM International Committee F45, are industrial vehicles that have capabilities to navigate, dock, avoid obstacles, and interact with other vehicles and systems all
Jason Kralj, Stephanie Servetas, Monique Hunter, Blaza Toman, Scott Jackson
Standard Reference Material (SRM) 2917 is intended for calibrating qPCR-based assays of fecal indicator bacteria (FIB) for assessing water quality. A unit of SRM 2917 consists of 6 Levels of linearized plasmid DNA. The length of DNA is approximately 4.4 kb
Peter Bajcsy, Mathias Hammer, Maximiliaan Huisman, Alex Rigano, Ulrike Boehm, James J. Chambers, Nathalie Gaudreault, Jaime A. Pimentel, Damir Sudar, Claire M. Brown, Alexander D. Corbett, Orestis Faklaris, Judith Lacoste, Alex Laude, Glyn Nelson, Roland Nitschke, Alison J. North, Renu Gopinathan, Farzin Farzam, Carlas Smith, David Grunwald, Caterina Strambio-De-Castillia
While the power of modern microscopy techniques is undeniable, rigorous record-keeping and quality control are required to ensure that imaging data may be properly interpreted (quality), reproduced (reproducibility), and used to extract reliable
The FY 2020 summary, prepared by the National Institute of Standards and Technology (NIST), compiles the reports provided by 22 participating agencies listed in Appendix A. In these reports, agencies document any new use of GUS in lieu of VCS during FY
Tina Butcher, Gloria Lee, Richard A. Harshman, Lisa Warfield, Shelby Bowers
NIST Handbook 44 was first published in 1949, having been preceded by similar handbooks of various designations and in several forms, beginning in 1918. NIST Handbook 44 is published in its entirety each year following the Annual Meeting of the National
Yulia Pustovalova, Frank Delaglio, Darien Craft, Hari Arthanari, Ad Bax, Martin Billeter, Mark Bostock, Hesam Dashti, Flemming Hansen, Sven Hyberts, Bruce Johnson, Krzysztof Kazimierczuk, Hengfa Lu, Mark W. Maciejewski, Tomas Miljenovic, Mehdi Mobli, Daniel Nietlispach, Vladislav Orekhov, Robert Powers, Xiaobo Qu, Scott Robson, David Rovnyak, Gerhard Wagner, Jinfa Ying, Matthew Zambrello, Jeffrey C. Hoch, David Donoho, Adam D. Schuyler
Although the concepts of non-uniform sampling (NUS) and non-Fourier spectral reconstruction in multidimensional NMR began to emerge four decades ago (Bodenhausen and Ernst, 1981; Barna and Laue, 1987), it is only relatively recently that NUS has become