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Edward Sisco, Amber Burns, Elizabeth Schneider, Charles R. Miller, IV, Laurel Bobka
As the challenges faced by drug chemists continue to persist, due the presence of synthetic opioids, novel psychoactive substances, and other emerging drugs, laboratories are continuing to look for new analytical approaches or techniques to ease the
Edward Sisco, Amber Burns, Elizabeth Schneider, Charles R. Miller, IV, Laurel Bobka
As the challenges faced by drug chemists continue to persist, due the presence of synthetic opioids, novel psychoactive substances, and other emerging drugs, laboratories are continuing to look for new analytical approaches or techniques to ease the
With the increased prevalence of novel psychoactive substances (NPSs), seized drug analysis has become more complex and challenging due, in part, to changing chemical structures and isomeric species. To assist in addressing these challenges a series of
Edward Sisco, Liz Robinson, Rebecca Mead, Charles R Miller
The presence of drug residue and drug background in a forensic context continues to be of interest for a variety of reasons ranging from its potential use as a means for presumptive identification to ensuring the safety and well-being of drug chemists
Travon Cooman, Colby E. Ott, Kourtney A. Dalzell, Amber Burns, Edward Sisco, Luis E. Arroyo
The continuous change of the drug landscape in the United States demands adaptation and incorporation of emerging analytical methods that preferably allow onsite screening but are also capable of supporting the analysis of seized drugs received at forensic
Haiying Guan, Yooyoung Lee, Lukas Diduch, Jesse Zhang, Ilia Ghorbanian Bajgiran, Timothee Kheyrkhah, Peter Fontana, Jonathan G. Fiscus
This document describes the online leaderboard public evaluation program, Open Media Forensics Challenge (OpenMFC) 2021-2022. In the report, first, the introduction, objectives, challenges, contributions, and achievements of the evaluation program are
A likelihood ratio (LR) system is defined as the entire pipeline of the measurement and interpretation processes where probabilistic genotyping software (PGS) is a piece of the whole LR system. To gain understanding on how two LR systems perform, a total
Michael Stocker, Johannes Soons, Thomas Renegar, Xiaoyu Zheng, Robert Thompson
Forensic laboratories considering optical 3D surface topography measurement for objective comparison and VCM face challenges with respect to cost, training, and quality assurance. The primary aim of this research was to address quality assurance issues
A method for the targeted confirmation of synthetic opioids and related compounds was developed and evaluated. Using an 11-component test solution a method was developed that focused on maximizing chromatographic separation and understanding the influence
Carina Hahn, Liansheng Larry Tang, Amy Yates, P. Jonathon Phillips
We evaluated the detailed, behavioral properties of face matching performance in two specialist groups: forensic facial examiners and super-recognizers. Both groups compare faces to determine identity with high accuracy and outperform the general
Jacqueline L. Mann, John L. Molloy, Mark Tyra, Kevin Pfeuffer, Barbara Fallon, JoAnn Buscaglia
Nondestructive microbeam X-ray fluorescence (µXRF) spectrometry has been used to investigate the elemental microheterogeneity in a candidate nuclear forensics reference material (RM), NIST SRM 4600: Surrogate Post-detonation Urban Debris. Using a principal
George W. Quinn, James Matey, Patrick J. Grother, Edward Watters
In most current applications of iris recognition, matching is done by computer algorithms. The dominant algorithms are based on the work of John Daugman and are well understood because of the extensive analysis in the literature of iris2pi (the shorthand
As the digital forensic field develops, taking steps towards ensuring a level of reliability in the processes implemented by its practitioners, emphasis on the need for effective testing has increased. In order to test, test datasets are required, but
MARYAM ABDUL-RAHMAN, Melissa M. Phillips, Walter Brent Wilson
NIST launched a CannaQAP in 2020 to improve the comparability of the analytical measurements in forensic and Cannabis (hemp and marijuana) testing laboratories. CannaQAP is an interlaboratory study mechanism that is similar to a proficiency testing scheme
Thomas P. Forbes, Jeffrey Lawrence, Changtong Hao, J Greg Gillen
Rapid screening for chemical traces of explosives and narcotics is widely used to support homeland security and law enforcement. These target compounds span a range of physicochemical properties from organic to inorganic, with preferential ionization
Xiaoyu (Sara) Yang, Pedatsur Neta, Yuri Mirokhin, Dmitrii V. Tchekhovskoi, Concepcion Remoroza, Meghan Burke Harris, Yuxue Liang, Sanford Markey, Stephen E. Stein
Annotating product ion peaks in tandem mass spectra is essential for evaluating spectral quality and validating peptide identification. This task is more complex for glycopeptides and is crucial for the confident determination of glycosylation sites in
Haiying Guan, Andrew Delgado, Yooyoung Lee, Amy Yates, Daniel Zhou, Timothee N. Kheyrkhah, Jonathan G. Fiscus
NIST released a set of Media Forensic Challenge (MFC) datasets developed in DARPA MediFor (Media Forensics) project to the public in the past 5 years. More than 300 individuals, 150 organizations, from 26 countries and regions worldwide use our datasets
A confined direct analysis in a real time mass spectrometry (DART-MS) system and method were developed for coupling directly with commercial electronic cigarettes for rapid analysis without sample preparation. The system consisted of a confining heated
Novel psychoactive substances (NPS) present a prominent and increasing concern for forensic laboratories across the country. Benzodiazepines, which are one class of NPS, have experienced a growing presence in the United States due, in part, to the
Facing increasing caseloads and an everchanging drug landscape, forensic laboratories have been implementing new analytical tools. Direct analysis in real time mass spectrometry (DART-MS) is often one of these tools because it provides a wealth of
The intentional or unintentional adulteration of baby formula with drugs of abuse is one of the many increasingly complex samples forensic chemists may have to analyze. This sample type presents a challenge because of a complex matrix that can mask the