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This environmental scan provides a broad view of the forensic science environment (as of 2023) and characterizes high-level historical and current issues and trends that might impact near and long-term decisions by forensic science research and standards
Our ultimate goal is to support the reliable identification of recent cannabis use by developing an infrastructure for evaluation, calibration, and quality control of cannabis breathalyzers akin to that which exists for alcohol breathalyzers. The primary
Analysis of ignitable liquids in fire debris samples can be a time-consuming process, from extraction of volatile compounds to instrumental analysis. Rapid gas chromatography-mass spectrometry (GC-MS) is a screening technique that can be utilized prior to
In digital forensics, file system analysis is a precursor task to event reconstruction. Often, unallocated content within a file system is content of interest to an investigation, and thus recognition, extraction, and ascription of unallocated files are
The passage of the 2018 Farm Bill has led to an estimated value of $824M for hemp production in the United States (US) in 2021 with an approximately 76% of it focused on floral hemp that is used to produce hemp-derived finished products such as smokable
The realm of analytical chemistry continues to struggle with defining and evaluating the limit of detection in analytical methods in the sense that a multitude of definitions, criteria, caveats, and...
Martin Baiker-Sorensen, Ivo Alberink, Laura Granell, Leen van der Ham, Erwin J.A.T. Mattijssen, Erich Smith, Johannes A. Soons, Peter Vergeer, Xiaoyu Alan Zheng
In this article an automated approach for interpretation of firearm mark comparison results is presented. First, similarity scores are derived for marks typically encountered on primers of fired cartridge cases: aperture shear striations as well as
The continued prevalence of xylazine in the illicit drug market has necessitated development of quick and simple methods for identification, including lateral flow immunoassays (also known as "test strips"), like those frequently used to detect fentanyl
Kristy Lenz, Stephen McDaniel, Dawn Rabbach, Becky Steffen, Douglas Storts, Robert McLaren
The VersaPlex™ 27PY System is a short tandem repeat (STR) multiplex from Promega that co-amplifies 27 loci. This six-dye multiplex was designed for casework samples and includes loci that meet database requirements for the US (CODIS) and Europe (ESS). The
Veruska Malave, Kavita Jeerage, Edward Garboczi, Tara Lovestead
Human studies provide valuable information on components or analytes recovered from exhaled breath, but there are limitations due to inter-individual and intra-individual variation. Future development and implementation of breath tests based on aerosol
Accreditation is a formal recognition by an independent third party/accreditation body that a forensic service provider such as a laboratory, unit, or agency,a meets standards. A standard is a requirement or guideline used to ensure that a process or
Arun Moorthy, Edward Erisman, Anthony J. Kearsley, Yuxue Liang, Edward Sisco, William E. Wallace
Fentanyl analogs are a class of designer drugs that are particularly challenging to unambiguously identify due to the mass spectral and retention time similarities of unique compounds. In this paper, we use agglomerative hierarchical clustering to explore
Jennifer Berry, Mary Gregg, Amanda Koepke, Reta Newman, Kavita Jeerage
Dynamic vapor microextraction (DVME) is a potential method for the extraction and concentration of ignitable liquid (IL) residue in fire debris. This low flow rate, purge-and-trap headspace concentration method collects IL vapors onto a chilled adsorbent
Donna J. Sirk, Andria Mehltretter, Meghan Prusinowski, Hal Arkes, David Flohr, Cedric Neumann, Scott Ryland, Tatiana Trejos
This interlaboratory study evaluated a guide for interpreting and reporting trace evidence examinations. The online survey aimed to assess the examiners' interpretation of casework scenarios designed by a subject matter expert panel (SMEP), specifically
With the sustained prevalence and introduction of emerging drugs throughout the world there is a need for continued development and maintenance of platforms that enable rapid identification and characterization of unknown compounds. To complement existing
Kavita Jeerage, Cheryle Beuning, Adam Friss, L. Cinnamon Bidwell, Tara Lovestead
An accurate cannabis breathalyzer based on quantitation of the psychoactive cannabinoid Δ9-tetrahydrocannabinol (THC) could be an important tool for deterring impaired driving. Such a device does not exist. Simply translating what is known about alcohol
Kevin Kiesler, Lisa Borsuk, Becky Steffen, Peter Vallone, Katherine Gettings
The U.S. National Institute of Standards and Technology analyzed a set of 1036 samples representing four major U.S. population groups (African American, Asian American, Caucasian, and Hispanic) with the ForenSeq DNA Signature Prep Kit, DNA primer mix B
Erin Russell, Edward Sisco, Allison Thomson, Jasmine Lopes, Dana Heilman, Margaret Rybak, Malik Burnett, Meghan Appley, Matthew Gladden
Maryland overdose deaths increased 16%, to a record high of 2,912 deaths during the 12-month period from July 2020 to June 2021. Illicitly manufactured fentanyl and/or fentanyl analogs* contributed to 84% of these overdose deaths.† Timely public health
Amy Yates, Jacqueline Cavazos, Geraldine Jeckeln, Ying Hu, Eilidh Noyes, Carina Hahn, Alice O'Toole, P. Jonathon Phillips
Forensic facial specialists identify faces more accurately than untrained participants on tests using high quality images of faces. Whether this superiority holds in more challenging conditions is not known. Here, we measured performance for forensic
Sarah Riman, Mirna Ghemrawi, Lisa Borsuk, Rami Mahfouz, Susan Walsh, Peter Vallone
This is the first study that characterizes the sequence-based allelic variations of 22 autosomal Short Tandem Repeat (aSTR) loci in a population dataset collected from Lebanon. Genomic DNA extracts from 195 unrelated Lebanese individuals were amplified
Over the past decade, seized drug analysis has been faced with several unique challenges that have pushed the limits of existing instrumentation and workflows. Practitioners are now often faced with increasing caseloads of complex samples that may contain
The Weight of Evidence (WoE) is defined to be the logarithm of the Bayes factor (BF) with base 10, which is generally with single point hypothesis rather than diffuse hypothesis. They are used in applications such as forensic science, etc. To statistically
Public health, public safety, and forensic science personnel continue to face the emergence of new compounds into the drug market. While focus is often put on the detection of new analogs of known illicit drugs, monitoring the changes in cutting agents and
Colby Ott, Amber Burns, Edward Sisco, Luis Eduardo Arroyo
Effective and rapid screening methods for seized drug analysis are crucial to ensure the safety of first responders and laboratory personnel, while reducing overall analysis time and improving reliability. The drug landscape has been overwhelmed by