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Reference Materials for DNA Analysis

Published

Author(s)

Barbara C. Levin, D J. Reeder

Abstract

Mention has already been made, in Section 5.1. Of the use of DNA-based techniques for control of microbiological DNA. In parallel to the work of ATCC the USA National Institute of Standards and Technology (NIST) developed three Standard Reference Materials (SRM 2390, SRM 2391 and SRM 2392) to provide quality assurance in the analysis of human DNA. Two of these SRMs- the DNA Profiling SRM 2390 and the PCR-based DNA Profiling SRM 2391, are intended for use in forensic and Parternity identifications. For instructional law enforcement, or non-clincal research purposes. They are not intended for any human/animal clinical diagnostic use. The third NIST SRM - 2392 - is for standardization and quality control when sequencing the entire or any segment of human mitochondrial DNA (16 569 base pairs) for forensic identification, disease diagnosis or mutation detection.
Citation
Reference Materials for DNA Analysis
Publisher Info
Book Chapter - Reference Materials for Chemical Analysis - Certification, Availability & Proper Use, Weinheim, NY

Keywords

DNA, forensic, human, mitochondrial DNA, polymerase Chain Reaction (PCR), restriction fragment length polymorphism, sequencing, short tanem repeats (STR), Standard Reference Materials

Citation

Levin, B. and Reeder, D. (2001), Reference Materials for DNA Analysis, Book Chapter - Reference Materials for Chemical Analysis - Certification, Availability & Proper Use, Weinheim, NY (Accessed June 13, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created February 28, 2001, Updated February 19, 2017