Shen, Z.
, Semancik, S.
and Sintim, H.
(2015),
Rapid DNA melting analyses using a microfabricated electrochemical platform, Analytica Chimica ACTA, [online], https://doi.org/10.1016/j.aca.2014.10.025
(Accessed December 10, 2024)
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Rapid DNA melting analyses using a microfabricated electrochemical platform
Published
Author(s)
, , Herman O. Sintim
Abstract
A new microscale platform is reported which is based on microfabrication methods that integrate thermal control and multi-electrode components to enable rapid temperature-dependent electrochemical measurements on small volume fluid samples. We demonstrate the device's capabilities by performing melting curve analyses for single-nucleotide polymorphism (SNP) detection.Citation
Analytica Chimica ACTA
Volume
853
Pub Type
Journals
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Keywords
DNA melting temperature: electrochemical melting, microfabrication, electrochemical platform, micro heater, single-nucleaotide polymorphism, methylene blue, square wave volammetry
Citation
Issues
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Created December 31, 2014, Updated October 12, 2021