Rapid DNA melting analyses using a microfabricated electrochemical platform
Zuliang Shen, Stephen Semancik, Herman O. Sintim
A new microscale platform is reported which is based on microfabrication methods that integrate thermal control and multi-electrode components to enable rapid temperature-dependent electrochemical measurements on small volume fluid samples. We demonstrate the device's capabilities by performing melting curve analyses for single-nucleotide polymorphism (SNP) detection.
, Semancik, S.
and Sintim, H.
Rapid DNA melting analyses using a microfabricated electrochemical platform, Analytica Chimica ACTA, [online], https://doi.org/10.1016/j.aca.2014.10.025
(Accessed June 3, 2023)