Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Primary and Secondary Droplet and Charge Transmission Characteristics of Desorption Electro-Flow Focusing Ionization

Published

Author(s)

Thomas P. Forbes, Timothy M. Brewer, John G. Gillen

Abstract

We present the investigation of droplet charging and charge transmission characteristics of an electro-flow focusing nozzle for desorption-based ambient ionization mass spectrometry. The electro-flow focusing geometry utilizes a concentrically flowing gas to focus a charged solvent stream through a small orifice, generating a steady liquid jet and charged droplet stream that impinges and ionizes the analyte and surface. Transmitted current measurements and a scaling analysis were incorporated to decouple analyte desorption and ionization from secondary droplet charging and to identify the regimes of operation, secondary droplet charge transport characteristics, and parameters limiting transmitted charge relevant for ambient ionization mass spectrometry.
Citation
Applied Physics Letters
Volume
102
Issue
21

Citation

Forbes, T. , Brewer, T. and Gillen, J. (2013), Primary and Secondary Droplet and Charge Transmission Characteristics of Desorption Electro-Flow Focusing Ionization, Applied Physics Letters, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=914743 (Accessed July 5, 2022)
Created May 28, 2013, Updated February 19, 2017