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Particle Size Measurements for Spheres With Diameters of 50 nm to 400 nm



Michelle K. Donnelly, George W. Mulholland


This paper describes a calibration service NIST is offering that measures the effective diameter of particles suspended in liquids using electrical differential mobility analysis. Measurements are for particles with diameters in the range of 50 nm to 400 nm. Electrical differential mobility analysis separates aerosol particles based on the particle size dependence of their electrical mobility. This measurement method was chosen because it offers lower uncertainty for particles smaller than 400 nm compared to other methods. Detailed descriptions of the calibration system, operating procedures, and analysis method are included. Customer information regarding test sample requirements, measurement uncertainty analysis, and quality control procedures is also included in the paper.
NIST Interagency/Internal Report (NISTIR) - 6935
Report Number


calibration services, differential mobility analysis, nanoparticles


Donnelly, M. and Mulholland, G. (2003), Particle Size Measurements for Spheres With Diameters of 50 nm to 400 nm, NIST Interagency/Internal Report (NISTIR), National Institute of Standards and Technology, Gaithersburg, MD, [online], (Accessed July 17, 2024)


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Created August 1, 2003, Updated November 10, 2018