NIST/NIH Vitamin D Metabolites Quality Assurance Program (VitDQAP): Final Report

Published

September 16, 2020

Author(s)

Katrice A. Lippa, Mary Bedner, Susan Tai, Carolyn Q. Burdette

Abstract

The National Institute of Standards and Technology (NIST) established a Vitamin D Metabolites Quality Assurance Program (VitDQAP) in collaboration with the National Institutes of Health Office of Dietary Supplements (NIH-ODS) in 2009. The VitDQAP at NIST administered twelve interlaboratory comparison exercises through 2016 for the measurement of vitamin D metabolites in human serum and plasma. The comparability of participant measurements for target analytes improved substantially over time through the development and promulgation of robust measurement technologies, identification and production of suitable reference materials, isolation and identification of measurement system biases, and support and encouragement of within-laboratory measurement quality control efforts. This VitDQAP Final Report summarizes the program and provides highlights of the twelve exercises conducted during the program’s eight-year lifetime.

Citation

NIST Interagency/Internal Report (NISTIR) - 8293

Report Number

8293

NIST Pub Series

NIST Interagency/Internal Report (NISTIR)

Pub Type

NIST Pubs

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DOI Link

Keywords

25 hydroxyvitamin D2, 25 hydroxyvitamin D3, 25 hydroxyvitamin DTotal, 3-epi-25 hydroxyvitamin D3, human serum and plasma, interlaboratory comparison study 25 hydroxyvitamin D2, 25 hydroxyvitamin D3, 25 hydroxyvitamin DTotal, 3-epi-25 hydroxyvitamin D3, human serum and plasma, interlaboratory comparison study Vitamin D, SRMs, QAPs, clinical

Citation

Lippa, K. , Bedner, M. , Tai, S. and Burdette, C. (2020), NIST/NIH Vitamin D Metabolites Quality Assurance Program (VitDQAP): Final Report, NIST Interagency/Internal Report (NISTIR), National Institute of Standards and Technology, Gaithersburg, MD, [online], https://doi.org/10.6028/NIST.IR.8293 (Accessed October 14, 2025)