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NIST Micronutrients Measurement Quality Assurance Program Analysis Tutorial



Katherine E. Sharpless, Jeanice M. Brown Thomas, David L. Duewer


Since 1984, the National Institute of Standards and Technology (NIST) has coordinated what is now known as the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure fat-soluble vitamins and carotenoids in human serum and plasma. The MMQAP has provided participants with measurement comparability assessment through use of interlaboratory studies, Standard Reference Materials (SRMs) and control materials, methods development and validation, workshops, and tutorials. This report reproduces the printed materials provided to participants in the 1997 Fat-Soluble Vitamin and Carotenoid Analysis Tutorials, the most recent in a series of hands-on training programs for laboratorians involved in fat-soluble vitamin-related analytes. Some of the tutorial material has been updated.
NIST Interagency/Internal Report (NISTIR) - 7880-40
Report Number


Analytical methods, Retinol, Tocopherols, Carotenoids, Human serum


Sharpless, K. , Brown, J. and Duewer, D. (2016), NIST Micronutrients Measurement Quality Assurance Program Analysis Tutorial, NIST Interagency/Internal Report (NISTIR), National Institute of Standards and Technology, Gaithersburg, MD, [online], (Accessed June 24, 2024)


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Created September 6, 2016, Updated November 10, 2018