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Nanomechanical mapping of the osteochondral interface with contact resonance force microscopy and nanoindentation

Published

Author(s)

Sara E. Campbell, Virginia L. Ferguson, Donna C. Hurley

Abstract

The bone-cartilage, or osteochondral, interface resists remarkably high shear stresses and rarely fails, yet its mechanical characteristics are largely unknown. A complete understanding of this hierarchical system requires mechanical-property information at both the length scale of the interface and that of the connecting tissues. Here, we combined nanoindentation and atomic force microscopy (AFM) methods to investigate the multiscale mechanical properties across the osteochondral interface. The indentation modulus M ranged from that of the subchondral bone [M = (22.8 ± 1.8) GPa] to that of hyaline articular cartilage [M = (5.7 ± 1.0) GPa] across a narrow transition region
Citation
ACTA Biomaterialia
Volume
8 (2012)

Citation

Campbell, S. , Ferguson, V. and Hurley, D. (2012), Nanomechanical mapping of the osteochondral interface with contact resonance force microscopy and nanoindentation, ACTA Biomaterialia, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=910832 (Accessed June 13, 2024)

Issues

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Created August 6, 2012, Updated February 19, 2017