Structural properties of polymeric scaffolds for tissue engineering play a key role in directing osteogenesis. These properties depend on the chemical nature and the fabrication process of biomaterial. There are many protocols for fabricating scaffolds for bone tissue engineering applications which afford control over scaffold topography. In addition, much work has demonstrated that cell differentiation is sensitive to topography at sizes ranging from nano- to micro- to macroscale. Thus, we have investigated the effect of different scaffold topographies on differentiation of human bone marrow stromal cells (hBMSCs).
Conference Dates: April 13-16, 2011
Conference Location: Orlando, FL
Conference Title: Society for Biomaterials
Pub Type: Conferences
polymer scaffold, stem cell, osteogenesis, nanofiber