DETERMINATION OF TRACE LEVEL CADMIUM IN SRM 3280 MULTIVITAMIN/MULTIELEMENT TABLETS VIA ISOTOPE DILUTION INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY

Published

November 15, 2013

Author(s)

Steven J. Christopher, R. Q. Thompson

Abstract

Cadmium was quantified at 80.15 ng/g ± 0.86 ng/g in NIST SRM 3280 Multivitamin/Multielement Tablets, using double isotope dilution mass spectrometry. The method described utilized various precipitation and solid phase extraction separation methodologies to isolate Cd from Sn and Mo, present respectively, at 11.1 mg/kg ± 0.9 mg/kg and 70.7 mg/kg ± 4.5 mg/kg in the vitamin matrix. This allowed for measurement of 111Cd/113Cd and 111Cd/114Cd isotope ratios using both quadrupole collision cell technology inductively coupled plasma mass spectrometry (Q-CCT-ICP-MS) or sector field (SF)-ICP-MS equipped with a desolvating nebulizer system to mitigate the MoO+ and MoOH+ molecular interferences and Sn isobaric interferences that typically affect the envelope of Cd isotopes.

Citation

Talanta

Pub Type

Journals

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DOI Link

Keywords

Cadmium, thiourea, solid phase extraction, desolvating nebulizer, collision cell ICP-MS, SF-ICP-MS

Citation

Christopher, S. and , R. (2013), DETERMINATION OF TRACE LEVEL CADMIUM IN SRM 3280 MULTIVITAMIN/MULTIELEMENT TABLETS VIA ISOTOPE DILUTION INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY, Talanta, [online], https://doi.org/10.1016/j.talanta.2013.04.068 (Accessed April 23, 2024)