DETERMINATION OF TRACE LEVEL CADMIUM IN SRM 3280 MULTIVITAMIN/MULTIELEMENT TABLETS VIA ISOTOPE DILUTION INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY
Steven J. Christopher, R. Q. Thompson
Cadmium was quantified at 80.15 ng/g ± 0.86 ng/g in NIST SRM 3280 Multivitamin/Multielement Tablets, using double isotope dilution mass spectrometry. The method described utilized various precipitation and solid phase extraction separation methodologies to isolate Cd from Sn and Mo, present respectively, at 11.1 mg/kg ± 0.9 mg/kg and 70.7 mg/kg ± 4.5 mg/kg in the vitamin matrix. This allowed for measurement of 111Cd/113Cd and 111Cd/114Cd isotope ratios using both quadrupole collision cell technology inductively coupled plasma mass spectrometry (Q-CCT-ICP-MS) or sector field (SF)-ICP-MS equipped with a desolvating nebulizer system to mitigate the MoO+ and MoOH+ molecular interferences and Sn isobaric interferences that typically affect the envelope of Cd isotopes.
and , R.
DETERMINATION OF TRACE LEVEL CADMIUM IN SRM 3280 MULTIVITAMIN/MULTIELEMENT TABLETS VIA ISOTOPE DILUTION INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY, Talanta, [online], https://doi.org/10.1016/j.talanta.2013.04.068
(Accessed November 28, 2023)