U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PUBLICATIONS

The Detection and Characterization of Ions, DNA and Proteins with Nanometer-Scale Pores

Published

Author(s)

John J. Kasianowicz, Jeffrey C. Lerman, Sarah E. Henrickson, Martin Misakian, Rekha Panchal, Kelly Halverson, Sina Bavari, Tam Nguyen, Rick Gussio, Devanand K. Shenoy, Vincent M. Stanford

Abstract

Protein ion channels are nanometer-scale pores that are central to many biological processes, including the sensing of a wide variety of molecules. They have also demonstrated their potential for use in the sensitive and selective detection of ions, the characterization of polynucleotides, and toxins as well as the screening of a therapeutic agent against a key lethal anthrax protein. Further advances in materials engineering, theory, and signal processing are needed to enable practical applications based on biological or synthetic nanopores.
Citation
Handbook of Biosensors and Biochips
Publisher Info
J. Wiley & Sons, Ltd., West Sussex, UK
Pub Type
Books

Keywords

analyte detection, anthrax, ion channels, nanopores, stochastic sensing
Nanoelectronics

Citation

Kasianowicz, J. , Lerman, J. , Henrickson, S. , Misakian, M. , Panchal, R. , Halverson, K. , Bavari, S. , Nguyen, T. , Gussio, R. , Shenoy, D. and Stanford, V. (2007), The Detection and Characterization of Ions, DNA and Proteins with Nanometer-Scale Pores, J. Wiley & Sons, Ltd., West Sussex, UK (Accessed December 2, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created November 30, 2007, Updated October 12, 2021