Characterization of a Series of Self-Assembled Monolayers of Alkylated 1-Thia(Ethylene Oxides)(4-8) on Gold

Published

August 8, 2000

Author(s)

David J. Vanderah, C Pham, S Springer, Vitalii I. Silin, Curtis W. Meuse

Abstract

Self-assembled monolayers (SAMs) of a series of linear thiols containing a1-thiaoligo(ethylene oxide) [TOEO] moiety, i.e., HS(EO)xR - where R = C10H21, EO = -CH2CH2O-, and x = 4 to 8 - were prepared on polycrystalline gold (Au) and characterized by visible spectroscopic ellipsometry (SE) and infrared spectroscopic ellipsometry (IRSE). The TOEO segment was found to adopt a 7/2 helical structure oriented normal to the substrate for x = 5 - 7. Different structures were found for the other compounds in this series. When x = 4, the TOEO segment adopts a predominantly trans-extended conformation. Whereas, when x = 8 the TOEO appears to be disordered with some helical conformation. Monolayer thicknesses determined by SE are consistent with these structural changes. A significant increase in disorder with extension of the hydrophilic segment by two ethylene oxide units from 6 to 8 is potentially valuable for protein reconstitution in supported hybrid bilayer constructs.

Citation

Langmuir

Volume

16

Issue

16

Pub Type

Journals

Keywords

hybrid bilayer membranes, self-assembled monolayers

Citation

Ross, D. , Pham, C. , Springer, S. , Silin, V. and Meuse, C. (2000), Characterization of a Series of Self-Assembled Monolayers of Alkylated 1-Thia(Ethylene Oxides)(4-8) on Gold, Langmuir (Accessed May 1, 2024)