In this work, we characterize a protein surface on a flexible polydimethylsiloxane substrate (PDMS) capable of undergoing strain. We compare the results from two different surface treatments: physically adsorbed laminin on PDMS and laminin deposited on silane treated PDMS. Immunofluorescence and x-ray reflectivity were used to measure the amount of laminin from each surface treatment. Vascular smooth muscle cell attachment and proliferation were compared between the methods. Additional work will concentrate on evaluating the robustness of surface treatments under strain.
Conference Dates: August 17-21, 2008
Conference Location: Philadelphia, PA
Conference Title: ACS Fall Meeting
Pub Type: Conferences
laminin, polydimethylsiloxane, smmoth muscle cells, X-ray reflectivity