CCQM–K62: Nutrients in Infant/Adult Formula – Vitamins

Published

April 24, 2010

Author(s)

Katherine E. Sharpless, Catherine A. Rimmer, Karen W. Phinney, Bryant C. Nelson, David L. Duewer, Stephen A. Wise

Abstract

Key Comparison CCQM-K62 was designed to enable demonstration of the equivalence in capabilities for measurement of vitamins in a food matrix. A milk-based fortified human infant/adult formula was selected as the matrix based upon material availability and relevance. Because vitamins were added to the CCQM-K62 study material in a single form and at levels significantly higher than those that would be naturally occurring in the milk base, the ability of a laboratory to measure the study vitamins is only indicative of a laboratory’s ability to measure vitamins in fortified foods. Target analytes were selected for study because of the ready availability of suitable standard materials and the range of their chemical properties: folic acid (vitamin B9) is a single water-soluble molecular entity that typically occurs at low levels and can be unstable, niacin (vitamin B3) is a single stable molecular entity and is typically present at higher concentrations than the other water-soluble vitamins, vitamin A has multiple molecular forms (including retinol and retinyl palmitate), is fat-soluble and typically occurs at relatively high levels.

Citation

Metrologia

Volume

47

Pub Type

Journals

Download Paper

DOI Link

Keywords

ccqm, k62, key comparison, vitamin, folic, niacin, retinol, retinyl, infant

Citation

Sharpless, K. , Rimmer, C. , Phinney, K. , Nelson, B. , Duewer, D. and Wise, S. (2010), CCQM–K62: Nutrients in Infant/Adult Formula – Vitamins, Metrologia, [online], https://doi.org/10.1088/0026-1394/47/1A/08016 (Accessed October 13, 2025)