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Biosynthetic origin of the 3-amino-2,5,7,8-tetrahydroxy-10-methylundecanoic acid moiety and absolute configuration of pahayokolides A and B

Published

Author(s)

Li Liu, Dan Bearden, Kathleen S. Rein

Abstract

Pahayokolide A is a cyclic undecapeptide from the cyanobacterium Lyngbya sp. The absolute configurations of the amino acids of pahayokolide A have been determined. Pahayokolide A contains the unusual α-hydroxy-β-amino acid, 3-amino-2,5,7,8- tetrahydroxy-10-methylundecanoic acid (Athmu). The starter unit for the biosynthesis of Athmu is derived from leucine which is extended further with three acetate units.
Citation
Journal of Natural Products
Volume
74
Issue
6

Keywords

cyanobacteria, natural product, NMR, spectroscopy

Citation

Liu, L. , Bearden, D. and Rein, K. (2011), Biosynthetic origin of the 3-amino-2,5,7,8-tetrahydroxy-10-methylundecanoic acid moiety and absolute configuration of pahayokolides A and B, Journal of Natural Products (Accessed June 22, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created June 7, 2011, Updated October 12, 2021