Journals

Testing Precision Limits of Neural Network-Based Quality Control Metrics in High-Throughput Digital Microscopy

January 26, 2022

Author(s)

Chris Calderon, Dean C. Ripple, Charudharshini Srinivasan, Youlong Ma, Michael J. Carrier, Theodore Randolph, Thomas O'Connor

Digital microscopy is used to monitor particulates such as protein aggregates within biologic pharmaceutical products. The digital images that result encode a...

Dynamics of Molecular Associates in Methanol/Water Mixtures

January 26, 2022

Author(s)

Yanqin Zhai, Peng Luo, Jackson Waller, Jeffrey L. Self, Leland Harriger, Y. Z., Antonio Faraone

The dynamics of molecular associates in methanol/water mixtures was investigated using quasielastic neutron scattering. By measuring the signal from four...

Intact, Commercial Lithium-Polymer Batteries: Spatially Resolved Grating-Based Interferometry Imaging, Bragg Edge Imaging, and Neutron Diffraction

January 25, 2022

Author(s)

Adam Brooks, Daniel Hussey, Kyungmin Ham, David Jacobson, Ingo Manke, Nikolay Kardjilov, Leslie G. Butler

We survey several neutron imaging and diffraction methods for non-destructive testing and evaluation of intact, commercial lithium-ion batteries. Specifically...

Photophysical engineering of fluorescent proteins: accomplishments and challenges of physical chemistry strategies

January 25, 2022

Author(s)

Srijit Mukherjee, Ralph Jimenez

Difference-Frequency Chirped-Pulse Dual-comb Generation in the THz Region: Magnification of Molecular Dynamics of Water Vapor Lines by >60,000

January 24, 2022

Author(s)

Jasper Stroud, David Plusquellic

A new difference frequency method to perform terahertz dual-comb spectroscopy is reported based on electro-optic phase modulators (EOMs) and two free-running...

Gut Microbe-Targeted Choline Trimethylamine Lyase Inhibition Improves Obesity Via Rewiring of Host Circadian Rhythms

January 24, 2022

Author(s)

Rebecca Schugar, Christy Gliniak, Lucas Osborn, William Massey, Naseer Sangwan, Anthony Horak, Rakhee Banerjee, Danny Orabi, Robert Helsley, Amanda Brown, Amy Burrows, Chelsea Finney, Kevin Fung, Frederick Allen, Daniel Ferguson, Anthony Gromovsky, Chase Neumann, Kendall Cook, Amy McMillan, Jennifer Buffa, James Anderson, Margarete Mehrabian, Maryam Goudarzi, Belinda Willard, Tytus Mak, Andrew Armstrong, Garth Swanson, Ali Keshavarzian, Jose Carlos Garcia-Garcia, Zeneng Wang, Aldons Lusis, Stanley Hazen, Mark Brown

Obesity has repeatedly been linked to reorganization of the gut microbiome, yet to this point obesity therapeutics have been targeted exclusively toward the...

Assessment of the precision, bias and numerical correlation of fitted parameters obtained by multi-spectrum fits of the Hartmann-Tran line profile to simulated spectra

January 24, 2022

Author(s)

Erin Adkins, Joseph T. Hodges

Although the Voigt profile has long been used to analyze absorption spectra, the quest for increased precision, accuracy and generality drives the application...

Realistic simulations of spin squeezing and cooperative coupling effects in large ensembles of interacting two-level systems

January 24, 2022

Author(s)

Julian Huber, Ana Maria Rey, Peter Rabl

We describe an efficient numerical method for simulating the dynamics of interacting spin ensembles in the presence of dephasing and decay. The method builds on...

Reverberation Chamber Metrology for Wireless Internet of Things Devices: Flexibility in Form Factor, Rigor in Test

January 22, 2022

Author(s)

Kate Remley, Anouk Hubrechsen, Sara Catteau

Internet of things (IoT) devices are proliferating in our connected world, with the number of devices expected to exceed 14 billion in 2023 [1] . Wireless IoT...

Dependence of Single-Wall Carbon Nanotubes Alignment on the Filter Membrane Interface in Slow Vacuum Filtration

January 22, 2022

Author(s)

Jeffrey Fagan, Angela R. Hight Walker, Adam Biacchi, Andrei Kolmakov, Zia Macdermid, William D. Rice, Joshua Walker, Thomas Searles

The recent development of slow vacuum filtration (SVF) technology has shown great promise for reproducibly producing high-quality, large-area aligned films of...

Determination of 11 Cannabinoids in Hemp Plant and Oils by Liquid Chromatography and Photodiode Array Detection

January 21, 2022

Author(s)

Walter Brent Wilson, MARYAM ABDUL-RAHMAN

Drug scheduling has directed the testing approaches for forensic laboratories since the 1970s when Cannabis (marijuana and hemp) and its psychoactive...

Interface History on Strain Field Evolution in Epoxy Resins

January 21, 2022

Author(s)

Edward Garboczi, Newell Moser, Jena McCollum, Jared Strutton, Abby Jennings, Brandon Runnels

To determine the viability of digital image correlation in the analysis of additively manufactured thermosets, we devised a testing method to examine the effect...

RNA reference materials with defined viral RNA loads of SARS-CoV-2 – A useful tool towards a better PCR assay harmonization

January 20, 2022

Author(s)

Laura Vierbaum, Nathalie Wojtalewicz, Vanessa Lindig, Ulf Dühring, Hans-Peter Grunert, Christian Drosten, Victor Corman, Daniela Niemeyer, Sandra Ciesek, Holger Rabenau, Annemarie Berger, Martin Obermeier, Andreas Nitsche, Janine Michel, Martin Mielke, Jim Huggett, Denise O'Sullivan, Simon Cowen, Megan Cleveland, Peter Vallone, Samreen Falak, Andreas Kummrow, Thomas Keller, Ingo Schellenberg, Heinz Zeichhardt, Martin Kammel

The outbreak and pandemic spread of SARS-CoV-2, the cause of the novel coronavirus disease (COVID-19), led to the need for a reliable detection method to track...

Measurement of sample stage error motions in cone-beam X-ray computed tomography instruments by minimization of reprojection errors

January 19, 2022

Author(s)

Massimiliano Ferrucci, Wim Dewulf, Alkan Donmez

Reconstruction algorithms in X-ray computed tomography assume a particular geometrical alignment of the instrument components. Misalignments in the actual...

New York City greenhouse gas emissions estimated with inverse modelling of aircraft measurements

January 19, 2022

Author(s)

Joseph Pitt, Israel Lopez Coto, Kristian Hajny, jay Tomlin, Robert Kaeser, Thilina Jayarathne, Brian Stirm, Cody Floerchinger, Christopher Loughner, Conor Gately, Lucy Hutyra, Kevin Gurney, Geoffrey Roest, Jianming Liang, Sharon Gourdji, Anna Karion, James Whetstone, Paul Shepson

Peak Fraction Purity and Chromatographic Resolution: Gaussian Peaks Revisited

January 19, 2022

Author(s)

Andre Striegel, Deborah Striegel

For incompletely resolved peak pairs, the purity of the chromatographic or fractographic fractions is oftentimes underestimated by the common user. This results...

Structure–Dilute Solution Property Relationships of Comblike Macromolecules in a Good Solvent

January 19, 2022

Author(s)

Robert Ivancic, Sara Orski, Debra Audus

The structural characterization of branched polymers still poses experimental challenges despite their technological potential. This lack of clarity is...

Quantitative Determination of Cell Viability Using Absorbance Microscopy

January 19, 2022

Author(s)

Greta Babakhanova, Stephen Zimmerman, Laura Pierce, Sumona Sarkar, Nicholas Schaub, Carl Simon Jr.

Cell viability is an essential measurement for cell therapy products. One of the most common tests is Trypan blue (TB) dye exclusion where blue-stained cells...

1-GHz mid-infrared frequency comb spanning 3 to 13 μm

January 18, 2022

Author(s)

Nazanin Hoghooghi, Sida XIng, Peter Chang, Daniel Lesko, Alexander Lind, Greg Rieker, Scott Diddams

Mid-infrared (MIR) spectrometers are invaluable tools for molecular fingerprinting and imaging. Among the available spectroscopic approaches, MIR dual-comb...

Predicting the plateau modulus from molecular parameters of conjugated polymers

January 18, 2022

Author(s)

Abigail Fenton, Renxuan Xie, Melissa Aplan, Youngmin Lee, Michael Gill, Ryan Fair, Fabian Kempe, Michael Sommer, Chad R. Snyder, Enrique Gomez, Ralph Colby

The relationship between Kuhn length lk, Kuhn monomer volume v0, and plateau modulus GN0 , initially proposed by Graessley and Edwards for flexible polymers...

FAIR Digital Object Demonstrators 2021

January 18, 2022

Author(s)

Peter Wittenburg, Ivonne Anders, Christophe Blanchi, Merret Buurman, Carole Goble, Jonas Grieb, Alex Hardisty, Sharif Islam, Thomas Jejkal, Tibor Kálmán, Christine Kirkpatrick, Laurence Lannom, Thomas Lauer, Giridhar Manepalli, Karsten Peters-von Gehlen, Andreas Pfeil, Robert Quick, Mark van de Sanden, Ulrich Schwardmann, Stian Soiland-Reyes, Rainer Stotzka, Zachary Trautt, Dieter Van Uytvanck, Claus Weiland, Philipp Wieder

This paper gives a summary of implementation activities in the realm of FAIR Digital Objects (FDO). It gives an idea which software components are robust and...

Understanding the dynamics of physiological changes, protein expression, and PFAS in wildlife

January 15, 2022

Author(s)

Jacqueline Bangma, T.C. Guillette, Paige Bommarito, Carla Ng, Jessica Reiner, Andrew Lindstrom, Mark Strynar

Per- and polyfluoroalkyl substances (PFAS) accumulation and elimination in both wildlife and humans is largely attributed to PFAS interactions with proteins...

Colloid-Like Solution Behavior of Computationally Designed Coiled Coil Bundlemers

January 15, 2022

Author(s)

Nairiti J. Sinha, Rui Guo, Rajkumar Misra, Jeffrey Fagan, Antonio Faraone, Christopher J. Kloxin, Jeffery G. Saven, Grethe V. Jensen, Darrin J. Pochan

The use of colloidal theory for describing protein-protein interactions is a topic of ongoing debate in the biophysical community. This contention stems from...

Interactions, Diffusion, and Membrane Fluctuations in Concentrated Unilamellar Lipid Vesicle Solution

January 14, 2022

Author(s)

Elizabeth Kelley, Emily Blick, Vivek Prabhu, Paul Butler, Michihiro Nagao

Lipid vesicles are widely used as models for cell membranes, hosts for membrane protein studies, and containers for hydrophilic molecules. The vesicle solutions...

Controlling Magnetic Configuration in Soft-Hard Bilayers Probed by Polarized Neutron Reflectometry

January 13, 2022

Author(s)

Nan Tang, Jung-Wei Liao, Kai Liu, Siu-Tat Chui, Timothy Ziman, Alexander Grutter

Hard/soft magnetic bilayer thin films have been widely used in data storage technologies and permanent magnet applications. The magnetic configuration and respo...

Magnetotransport and magnetic textures in Ho/FeCoGd/β-W multilayers

January 12, 2022

Author(s)

Ramesh Budhani, Vinay Sharma, Ezana Negusse, Jacob Casey, Arjun Pathak, Jerzy Sadowski, Brian Kirby

The enhancement of interfacial Dzyaloshinskii – Moriya Interaction (DMI) in magnetic multilayers results in the stabilization of topological spin textures like...

Noble-metal dark-edge fermiology: core-hole memory and the "Zeeman Auger" effect

January 12, 2022

Author(s)

Eric L. Shirley, Joseph Woicik, Conan Weiland, Ahmed Rumaiz, Charles Cardot, Joshua Kas, John Rehr

Gold and platinum have the face-centered-cubic crystal structure, are considered noble metals, and differ by one in atomic number. Near-edge M4,5 x-ray...

A Convolutional Neural Networks-Based Approach for Texture Directionality Detection

January 12, 2022

Author(s)

Marcin Kociolek, Michal Kozlowski, Antonio Cardone

The perceived texture directionality is an important, not fully explored image characteristic. In many applications texture directionality detection is of...

Global perspectives of the bulk electronic structure of URu2Si2 from angle-resolved photoemission

January 11, 2022

Author(s)

Jonathan Denlinger, J.-S. Kang, L. Dudy, J. Allen, Kyoo Kim, J.-H. Shim, Kristjan Haule, J. Sarrao, Nicholas Butch, M. Maple

Previous high-resolution angle-resolved photoemission (ARPES) studies of URu 2Si 2 have characterized the temperature-dependent behavior of narrow-band states...

Using Co-simulation between EnergyPlus and CONTAM to Evaluate Recirculation-based, Demand-controlled Ventilation Strategies in an Office Building

January 11, 2022

Author(s)

Maria Alonso, William Stuart Dols

A coupled energy, airflow, and contaminant transport building model was developed using co-simulation between EnergyPlus and CONTAM. The model was used to...