NIST provides NOAA the capacity to accurately assess exposure of marine animals to stressors and a mechanism for retrospective analysis of marine animal tissues. This work enhances NOAA's capability to manage marine animal populations. Federally protected marine species are impacted by many man-made and non man-made factors that can lead to declines in their populations. The information provided by NIST helps NOAA to make informed decisions about which stressors lead to the greatest harm, and whether these factors can be alleviated. Methods for assessing contaminants and disease are continually improving. The availability of banked samples from protected marine species allows for the ability to assess past levels of contamination, disease, and physiological markers of health. Management actions by NOAA based on information provided by NIST will help to conserve protected species for future generations.