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Precision medicine


NIST is playing a pivotal role in helping to define the measurements and standards needed to ensure the promise of precision medicine, which is an emerging approach for disease prevention and treatment that takes into account an individual’s genes, environment and lifestyle.

NIST and the Promise of Precision Medicine
NIST and the Promise of Precision Medicine

News and Updates

Projects and Programs

NIST Genome Editing Consortium

The National Institute of Standards and Technology Genome Editing Consortium addresses the measurements and standards needed to increase confidence and lower

NIST Genome Editing Program

Genome Editing technologies have transformed the potential of biosciences and biotechnology, by providing precision engineering tools that enable modifications

Genome in a Bottle

Consortium hosted by NIST dedicated to authoritative characterization of benchmark human genomes. Sign up for General GIAB and Analysis Team email lists


Digital PCR for the Characterization of Reference Materials

Megan Cleveland, Hua-Jun He, Mojca Milavec, Young-Kyung Bae, Peter Vallone, Jim Huggett
Well characterized reference materials are essential to ensuring the harmonization and accuracy of nucleic acid-based tests (such as qPCR); digital PCR (dPCR)

Accelerator-Based Production of Scandium Radioisotopes for Applications in Prostate Cancer: Toward Building a Pipeline for Rapid Development of Novel Theranostics

Jason Meier, Hannah Zhang, Richard Freifelder, Mohammed Bhuiyan, Phillip Selman, Megan Mendez, Pavithra Kankanamalage, Thomas Brossard, Antonino Pusateri, Hsiu-Ming Tsai, Lara Leoni, Sagada Penano, Kaustab Ghosh, Brittany Broder, Erica Markiewicz, Amy Renne, Walter Stadler, Ralph Weichselbaum, Jerry Nolen, Chien-Min Kao, Satish Chitneni, David Rotsch, Russell Szmulewitz, Chin-Tu Chen
In the field of nuclear medicine, the β+ emitting 43Sc and β- emitting 47Sc are promising candidates in cancer diagnosis and targeted radionuclide therapy (TRT)

A Draft Human Pangenome Reference

Wen-Wei Liao, Mobin Asri, Jana Ebler, Jennifer McDaniel, Nathanael David Olson, Justin Wagner, Justin Zook, Erik Garrison, Tobias Marschall, Ira Hall, Heng Li, Benedict Paten
Here the Human Pangenome Reference Consortium presents a first draft of the human pangenome reference. The pangenome contains 47 phased, diploid assemblies from