Dr. Pettibone is interested in reactions occurring on natural and engineered nanomaterial surfaces using spectroscopic, spectrometric, light scattering or other developed tools (e.g., assays) to investigate the chemical and physical changes that occur. The current research focuses on the formation, stability, and transformation of nanomaterials in complex environments to improve predictive capabilities for fate and improved design of safe and effective materials. His approach to address knowledge gaps regarding nanoparticle stability, efficacy, and fate in environmental and biological systems is to identify the major pathways of transformations after introduction into natural and engineered systems, which provides critical information for evaluating efficacy of remediation applications, biomedical applications and necessary for eco-toxicity testing. Through both the development and validation of general analytical methods to follow the entire mass distribution and elucidating the role interfacial surface chemistry contributes to the observable pathways, better inputs for modeling fate and improved understanding of impact and efficacy can be achieved. The ability to measure the mass distribution should result in improved design principles for improved application and limit the need for iterative approaches. Validation of the methods to ensure the measurands are accurately detected, characterized, and quantified, is rigorously assessed using a suite of analytical tools, which directly interrogate both the physical and chemical structure with limited perturbation.
J. M. Pettibone and J. Liu, In Situ Methods for Monitoring Silver Nanoparticle Sulfidation in Simulated Waters. Environ. Sci. Technol., 2016, 50, 11145-11153. http://dx.doi.org/10.1021/acs.est.6b03023
J. Gigault, J. M. Pettibone, C. Schmitt and V. A. Hackley, Rational strategy for characterization of nanoscale particles by asymmetric-flow field flow fractionation: A tutorial. Anal. Chim. Acta, 2014, 809, 9-24. http://dx.doi.org/10.1016/j.aca.2013.11.021
J. M. Pettibone, J. Gigault and V. A. Hackley, Discriminating the States of Matter in Metallic Nanoparticle Transformations: What Are We Missing? ACS Nano, 2013, 7, 2491-2499. http://dx.doi.org/10.1021/nn3058517
J. M. Pettibone and J. W. Hudgens, Gold Cluster Formation with Phosphine Ligands: Etching as a Size-Selective Synthetic Pathway for Small Clusters? ACS Nano, 2011, 5, 2989-3002. http://dx.doi.org/10.1021/nn200053b
J. M. Pettibone and J. W. Hudgens, Predictive Gold Nanocluster Formation Controlled by Metal-Ligand Complexes. Small, 2012, 8, 715-725. http://dx.doi.org/10.1002/smll.201101777
NRC postdoctoral fellowship, 2009