Frank Marí has worked extensively with peptides and proteins of marine origin; especially those from predatory venomous mollusks belonging to the genus Conus (cone snails), using an assortment of bioanalytical techniques to biochemically and functionally characterize components of interest. As part of these efforts, he has developed NMR-based structural techniques to study neuroactive marine peptides using nanomolar quantities directly isolated from their natural sources. Frank is also engaged in the development of mass spectrometry and bioinformatics based workflows for "venomics", a comprehensive approach for the screening and identification of neuroactive compounds from the venom of marine organisms. Through venomics, the aim is to intensify the discovery process of marine compounds of neuropharmacological importance and evaluate their potential in human health applications. Frank leads the recently created Marine Biochemical Sciences Team at Hollings Marine Laboratory. The mission of the team is to perform state-of-the-art bioanalytical measurements in samples of marine origin, particularly those samples that have environmental and human health impact.