Frank Heinrich

Publications

Structural and Biophysical Properties of Farnesylated KRas Interacting with the Chaperone SmgGDS-558

October 4, 2022

Author(s)

Dennis J. Michalak, Bethany Unger, Ellen Lorimer, Alexander Grishaev, Carol Williams, Frank N. Heinrich, Mathias Losche

KRas is a small GTPase and membrane-bound signaling protein. Newly synthesized KRas is posttranslationally modified with a membrane-anchoring prenyl group. KRas

Copper‑binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption

June 16, 2021

Author(s)

Fatih Comert, Frank N. Heinrich, Ananda Chowdhury, Mason Schoeneck, Caitlin Darling, Kyle Anderson, M. Daben J. Libardo, Alfredo Angeles‑Boza, Vitalii I. Silin, Myriam Cotten, Mihaela Mihailescu

In the search for novel broad‑spectrum therapeutics to fight chronic infections, inflammation, and cancer, host defense peptides (HDPs) have garnered increasing

Information Gain from Isotopic Contrast Variation in Neutron Reflectometry on Protein-Membrane Complex Structures

June 1, 2020

Author(s)

Frank Heinrich, Paul Kienzle, David P. Hoogerheide, Mathias Loesche

We apply a framework to quantify information gain from neutron or x-ray reflectometry experiments (Treece et al., 2019), in an in-depth investigation into the

Spatial Distribution of PEO-PPO-PEO Block copolymer and PEO Homopolymer in Lipid Bilayers

April 7, 2020

Author(s)

Mihee Kim, Frank Heinrich, Greg Haugstad, Guichuan Yu, Guangcui Yuan, Sushil K. Satija, Wenjia Zhang, Hannah S. Seo, Joseph M. Metzger, Samira M. Azarin, Timothy P Lodge, Benjamin J. Hackel, Frank S. Bates

Maintaining the integrity of cell membranes is indispensable for cellular viability. Poloxamer 188 (P188), a poly(ethylene oxide)-b-poly(propylene oxide)-b-poly

Accurate Background Correction in Neutron Reflectometry Studies of Soft Condensed Matter Films in Contact with Fluid Reservoirs

February 1, 2020

Author(s)

David P. Hoogerheide, Frank Heinrich, Brian B. Maranville, Charles F. Majkrzak

Neutron reflectometry (NR) is a powerful method of looking at the structures of multilayered thin films-including biomolecules on surfaces, particularly

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Frank Heinrich (Assoc)

Publications