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Edward Sisco (Fed)

Research Chemist

Ed Sisco has been a research chemist within the Surface and Trace Chemical Analysis Group since 2014.  His research has focused on mass spectrometry systems for forensics, homeland security, and other applications. Ed has extensive knowledge in traditional mass spectrometry systems (GC-MS, LC-MS, IC-MS), secondary ion mass spectrometry (SIMS), and ambient ionization mass spectrometry (AI-MS) such as DART-MS, DESI-MS, DEFFI-MS, etc. Ed's current research efforts are focused on addressing measurement challenges in forensic chemistry, providing fundamental measurements to address the opioid epidemic, and increasing awareness of the advantages of implementing AI-MS in screening and laboratory environments.  He is a member of the Fire Debris & Explosives subcommittee on OSAC, a member of ASTM, and an associate editor for Forensic Chemistry.


  • 2023 - American Society of Crime Laboratory Directors President’s Medallion Award
  • 2021 - Samuel J. Heyman Service to America Medal (Sammie): Emerging Leader Finalist
  • 2018 - NIST Bronze Metal Award

Selected Publications


National Institute on Drug Abuse Clinical Trials Network Meeting Report: Managing Patients Exposed to Xylazine-Adulterated Opioids in Emergency, Hospital and Addiction Care Settings

Jeanmarie Perrone, Rachel Haroz, Joseph D'Orazio, Giacomo Gianotti, Jennifer Love, Matthew Salzman, Margaret Lowenstein, Ashish Thakar, Stephanie Klipp, Lisa Rae, Megan Reed, Edward Sisco, Rachel Wightman, Lewis Nelson
Used as a veterinary sedative and not approved for human use, xylazine has been increasingly linked with opioid overdose deaths in the United States. A growing
Created October 9, 2019, Updated January 5, 2024