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Christina Bergonzo

Research Chemist

My current research includes developing computational methods to understand RNA conformational preferences. These include multi-dimensional replica exchange simulations of RNA tetranucleotide, tetraloop, and hairpin systems under various force field conditions. This work will be extended and combined with new experimental data, including small and wide angle X-ray scattering and NMR, to develop and refine empirical modifications to a fixed charge nucleic acid force field.


  • NRC Postdoctoral Fellowship, January 2017 – January 2019
  • Postdoctoral Travel Assistance Award, University of Utah Graduate School, Summer 2014
  • Chemistry Award for Outstanding Doctoral Student, Stony Brook University, Spring 2012
  • Chemical Computing Group Excellence Award, Spring ACS 2011
  • NSF IGERT Trainee, Summer 2007 – 2011


Structural Insights into DNA-Stabilized Silver Clusters

Danielle Schultz, Robert G. Brinson, Fahriye N. Sari, Jeffrey A. Fagan, Christina Bergonzo, Nancy J. Lin, Joy P. Dunkers
The structure and dynamics of Ag complexes derived from single stranded DNA (ssDNA) is less understood than their double stranded (dsDNA) counterparts despite

A Single Amino Acid Substitution Alters ClpS Binding Specificity

Christina Bergonzo, Jennifer A. Tullman, Kunal Dharmadhikari, Emily Samuels, Makenzie Christensen
ClpS is a small protein currently under development as a probe for detecting specific N-terminal amino acids of peptides. In order for ClpS to be used in this
Created July 30, 2019, Updated September 10, 2019