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Christina Bergonzo ()

Research Chemist

My current research includes developing computational methods to understand RNA conformational preferences. These include multi-dimensional replica exchange simulations of RNA tetranucleotide, tetraloop, and hairpin systems under various force field conditions. This work will be extended and combined with new experimental data, including small and wide angle X-ray scattering and NMR, to develop and refine empirical modifications to a fixed charge nucleic acid force field.

Awards

  • NRC Postdoctoral Fellowship, January 2017 – January 2019
  • Postdoctoral Travel Assistance Award, University of Utah Graduate School, Summer 2014
  • Chemistry Award for Outstanding Doctoral Student, Stony Brook University, Spring 2012
  • Chemical Computing Group Excellence Award, Spring ACS 2011
  • NSF IGERT Trainee, Summer 2007 – 2011

Publications

Effects of Glycans and Hinge on Dynamics in the IgG1 Fc

Author(s)
Christina Bergonzo, J. Todd Hoopes, Zvi Kelman, David Travis Gallagher
The crystallizable fragment (Fc) domain of immunoglobulin subclass IgG1 antibodies is engineered for a wide variety of pharmaceutical applications. Two
Created July 30, 2019, Updated December 8, 2022