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Bruce A Benner Jr. (Fed)

Research Chemist

Bruce worked first on gas and liquid chromatographic measurements of polycyclic aromatic hydrocarbons (PAHs) in a number of natural matrix materials, including Standard Reference Materials (SRMs). He also researched supercritical fluid extraction (SFE) in both off-line and on-line applications, contributing to a more realistic view on the effectiveness of this extraction technique in environmental applications. As part of a continuing other agency project, Bruce has worked on refining techniques for gleaning both qualitative and semi-quantitative organic chemical information from very small samples (≤ μg). Most of his experience is in gas chromatography with mass spectrometric detection (GC/MS) in both electron impact ionization (EI) and chemical ionization (CI) modes, and he has used GC/MS in the certification of a number of SRMs.  Bruce has developed and refined GC/MS methods for the measurement of explosives, fatty acids, metabolites, and plasticizers in a variety of samples and SRMs and is the technical contact for a large variety of SRMs from air particulate matter to frozen human serum.


  • Department of Commerce, Bronze Medal Award, 2012

Membership and Professional Activities

  • American Chemical Society, member, 1989-present
  • American Society for Mass Spectrometry


Metabolomics Test Materials for Quality Control: A Study of a Urine Materials Suite

Dan Bearden, David A. Sheen, Yamil Simon, Bruce A. Benner Jr., Werickson Fortunato de Carvalho Rocha, Niksa Blonder, Katrice A. Lippa, Richard Beger, Laura Schnackenberg, Jinchun Sun, Khyati Mehta, Amrita Cheema, Haiwei Gu, Ramesh Marupaka, Nagana Gowda, Daniel Raftery
There is a lack of experimental reference materials and standards for metabolomics measurements, such as urine, plasma, and other human fluid samples. Reasons

Health Assessment Measurements Quality Assurance Program: Exercise 1 Final Report

Chuck Barber, Bruce A. Benner Jr., Jeanice M. Brown Thomas, Carolyn Burdette, Johanna Camara, Stephen E. Long, Jacolin Murray, Melissa M. Phillips, Benjamin Place, Kate Rimmer, Laura J. Wood, Susan Tai, Siva K. Chinthalapati, Lee L. Yu
The NIST Health Assessment Measurements Quality Assurance Program (HAMQAP) was launched in collaboration with the National Institutes of Health (NIH) Office of

Development of Urine Standard Reference Materials for Metabolites of Organic Chemicals Including Polycyclic Aromatic Hydrocarbons, Phthalates, Phenols, Parabens, and Volatile Organic Compounds

Michele M. Schantz, Bruce A. Benner Jr., Nathanael A. Heckert, Lane C. Sander, Katherine E. Sharpless, Stacy S. Schuur, Stephen A. Wise
Two new Standard Reference Materials (SRMs), SRM 3672 Organic Contaminants in Smokers’ Urine (Frozen) and SRM 3673 Organic Contaminants in Non-Smokers’ Urine
Created August 24, 2018, Updated December 8, 2022