Twenty-two phthalate diesters and organophosphate triesters have been determined in Standard Reference Material (SRM) 2585 Organic Contaminants in House Dust. Ultrasonic assisted solvent extraction and Solid Phase Extraction on a Florisil adsorbent were used as clean-up combined with analysis using gas chromatography - tandem mass spectrometry in positive ion chemical ionization mode. Seven phthalates were detected in the concentration range 1 - 570 υg/g. Diethylhexyl phthalate was the major phthalate with a concentration of 570 υg/g dust. Twelve organophosphates were detected in the SRM 2585. Tri(2-butoxyethyl) phosphate was the dominating phosphate with a concentration of 82 υg/g and nine phosphates with concentrations around 1 υg/g dust. Three phosphates were detected but were below LOQ and three were below a MDL of 0.001 υg/g. The applied extraction and clean-up method was evaluated for the analysis of SRM 2585. Extraction yield was ≥ 99%, except for TCEP (97%) and DEP (98,5 %). The problem of calibration curvature is addressed, and it is shown how to improve the analysis by using deuterated standards. To our knowledge this is the first report of the concentrations of phthalates esters in SRM 2585 House Dust as well as the determination of as many as fourteen organophosphate triesters.
Citation: Analytical and Bioanalytical Chemistry
Issue: 10th Anniversary
Pub Type: Journals
Organophosphate esters, phthalate esters, Standard Reference Material 2585, Organic Contaminants in House Dust, NIST