Campbell, S.
, Ferguson, V.
and Hurley, D.
(2012),
Nanomechanical mapping of the osteochondral interface with contact resonance force microscopy and nanoindentation, ACTA Biomaterialia, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=910832
(Accessed October 15, 2025)
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Nanomechanical mapping of the osteochondral interface with contact resonance force microscopy and nanoindentation
Published
Author(s)
, Virginia L. Ferguson,
Abstract
The bone-cartilage, or osteochondral, interface resists remarkably high shear stresses and rarely fails, yet its mechanical characteristics are largely unknown. A complete understanding of this hierarchical system requires mechanical-property information at both the length scale of the interface and that of the connecting tissues. Here, we combined nanoindentation and atomic force microscopy (AFM) methods to investigate the multiscale mechanical properties across the osteochondral interface. The indentation modulus M ranged from that of the subchondral bone [M = (22.8 ± 1.8) GPa] to that of hyaline articular cartilage [M = (5.7 ± 1.0) GPa] across a narrow transition regionCitation
ACTA Biomaterialia
Volume
8 (2012)
Pub Type
Journals
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Citation
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Created August 6, 2012, Updated February 19, 2017