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PUBLICATIONS

Chemically-Sensitive Bioimaging with Coherent Raman Scattering

Published

Author(s)

Charles H. Camp, Marcus T. Cicerone

Abstract

Raman scattering provides an intrinsic fingerprint of chemical composition. Spontaneous Raman spectroscopy has been used for many decades to interrogate biological materials and systems, but is not widely used for imaging due to relatively slow signal acquisition. Coherent Raman imaging (CRI) technologies have evolved over the last 15 years to provide the same rich chemical information but orders-of-magnitude faster. CRI methods are now poised to begin emerging as widely used tools for obtaining functional information in a label-free manner from biological systems. We briefly review the development and application of these methods.
Citation
Nature Photonics
Volume
9
Pub Type
Journals

Download Paper

DOI Link

Keywords

CARS, BCARS, Review, Coherent Raman Imaging, Nonlinear microscopy, Nonlinear Spectroscopy
Analytical chemistry, Biological physics, Optical physics and communications and Spectroscopy

Citation

Camp, C. and Cicerone, M. (2015), Chemically-Sensitive Bioimaging with Coherent Raman Scattering, Nature Photonics, [online], https://doi.org/10.1038/nphoton.2015.60 (Accessed October 13, 2025)

Issues

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Created April 29, 2015, Updated November 10, 2018
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