Travis Gallagher studied Electrical Engineering and Computer Science at MIT, and then Biochemistry at the University of Texas (Ph.D. 1990). After a National Research Council postdoctoral fellowship in protein crystallography with Gary Gilliland, he joined NIST's Biotechnology Division, leading to his present position at NIST/IBBR.
Travis's interests in crystal growth, structure determination and the functional properties of proteins helped prepare him to grapple with key measurement and modeling challenges in the Biomolecular Measurement Dvision. His work advances the NIST mission by providing measurements and structural data on biomolecular models that are widely used in the commercial development of new protein medicines like antibodies and T cell receptors.
For example, our 20659-atom 3D coordinate model of the NISTmAb monoclonal antibody standard reference material, based on extensive collaboration as well as Travis's crystallography and modeling, serves as a resource for the structural engineering that underlies the development of new immunotherapies. Another example is structural measurements of T cell receptors, which, like antibodies, are both vital to human health and in development for innovative medical applications. Beyond those specific projects, he collaborates widely with both UMD and NIST researchers on problems involving biomolecular measurements and models.