Uncertainty quantification

News and Updates

Where Once Were Black Boxes, NIST’s New LANTERN Illuminates

June 22, 2022

Researchers at the National Institute of Standards and Technology (NIST) have developed a new statistical tool that they have used to predict protein function.

A New Harmony: NIST Researchers Develop a Universal Method for Calculating the Resonances of Oscillators

September 15, 2021

The natural, or resonance, frequency at which a simple harmonic oscillator vibrates reveals with exquisite sensitivity the essential properties of the physical

Making the DNA Melt Curve More Accurate

August 18, 2020

DNA is not only the blueprint of life; it has become the backbone for making tiny structures that can be inserted into the human body to diagnose and treat

Projects and Programs

Autonomous Scanning Droplet Cell

Ongoing

We use autonomous experimentation to elucidate the role of composition, processing, and microstructure on the aqueous corrosion of complex metal alloys. To do

Additive Manufacturing Part Qualification

Ongoing

Critical parts for defense, aerospace, and medical applications must be formally qualified prior to use. Currently, extensive empirical testing consisting of

Data Driven Decision Support for Additive Manufacturing

Ongoing

“Digital disruption is a change in industry triggered by advances in information and communications technology. During the next few years, the technologies

Consistency Analysis and Uncertainty in ‘omic Data

Ongoing

As ‘omics moves into industrial and commercial applications, there is a need for quality and process control to ensure safety and efficacy of products and

Publications

A Way of Estimating the Standard Errors of Bayes Factor and Weight of Evidence – A Case Study (Theoretical Framework)

March 27, 2023

Author(s)

Jin Chu Wu, John M. Libert

The Weight of Evidence (WoE) is defined to be the logarithm of the Bayes factor (BF) with base 10, which is generally with single point hypothesis rather than

Value Assignment and Uncertainty Evaluation for Anion and Single-Element Reference Solutions

February 27, 2023

Author(s)

Brian Lang, John L. Molloy, Thomas W. Vetter, Shaun Kotoski, Antonio Possolo

The National Institute of Standards and Technology (NIST) assigns certified values to the mass fractions of individual elements in single-element solutions

Using Monte Carlo Methods to Compute the Uncertainty of Fracture Toughness and Fracture Resistance Curves

February 3, 2023

Author(s)

Lucas Koepke, Dash Weeks, Jolene D. Splett

The uncertainty of fracture toughness and associated fracture resistance curves for single edge-notched tension (SE(T) or SENT) specimens is a key component

Leveraging Theory for Enhanced Machine Learning

August 26, 2022

Author(s)

Debra Audus, Austin McDannald, Brian DeCost

The application of machine learning to the materials domain has traditionally struggled with two major challenges: a lack of large, curated data sets and the

Software

Cost Assessment Tool for Sustainable Manufacturing (CATS)

August 1, 2022

This tool uses techniques from ASTM E3200 for evaluating manufacturing investments from the perspective of environmentally sustainable manufacturing by pairing

Tools and Instruments

Reference Ballistic Chronograph

The NIST-developed reference ballistic chronograph (RBC) provides repeatable measurements of the speed of a bullet that will impact a test article, such as