Universal Spectrum Identifier for mass spectra

Published

July 2, 2021

Author(s)

Eric Deutsch, Yasset Perez-Riverol, Jeremy Carver, Shin Kawano, Luis Mendoza, Tim Van Den Bossche, Ralf Gabriels, Pierre-Alain Binz, Benjamin Pullman, Zhi Sun, Jim Shofstahl, Wout Bittremeieux, Tytus Mak, Joshua Klein, Yunping Zhu, Henry Lam, Juan Antonio Vizcaino, Nuno Bandeira

Abstract

Mass spectra provide the ultimate evidence to support the findings of mass spectrometry proteomics studies in publications, and it is therefore crucial to be able to trace the conclusions back to the spectra. The Universal Spectrum Identifier (USI) provides a standardized mechanism for encoding a virtual path to any mass spectrum contained in datasets deposited to public proteomics repositories. USI enables greater transparency of spectral evidence, with more than 1 billion USI identifications from over 3 billion spectra already available through ProteomeXchange repositories.

Citation

Nature Methods

Pub Type

Journals

Download Paper

https://doi.org/10.1038/s41592-021-01184-6

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Keywords

Proteomics Standards Initiative, PSI, mass spectrometry, proteomics, Universal Spectrum Identifier, USI, standards.

Citation

Deutsch, E. , Perez-Riverol, Y. , Carver, J. , Kawano, S. , Mendoza, L. , Van Den Bossche, T. , Gabriels, R. , Binz, P. , Pullman, B. , Sun, Z. , Shofstahl, J. , Bittremeieux, W. , Mak, T. , Klein, J. , Zhu, Y. , Lam, H. , Vizcaino, J. and Bandeira, N. (2021), Universal Spectrum Identifier for mass spectra, Nature Methods, [online], https://doi.org/10.1038/s41592-021-01184-6, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=932089 (Accessed December 6, 2024)