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Ultrasonic Estimation of Mechanical Properties of Pulmonary Arterial Wall under Normoxic and Hypoxic Conditions

Published

Author(s)

Kendall Waters, O M. Mukdadi

Abstract

Secondary pediatric pulmonary hypertension is a disease that could benefit from improved ultrasonic diagnostic techniques. We perform high-frequency in vitro ultrasound measurements (25 MHz to 100 MHz) on fresh and fixed pulmonary arterial walls excised from normoxic and hypoxic Long-Evans rat models. Estimates of the elastic stiffness coefficients are determined from measurements of the speed of sound. Preliminary results indicate that hypoxia leads to up to a 20 % increase in stiffening of the pulmonary arterial wall.
Conference Dates
July 25-30, 2004
Conference Location
Golden, CO
Conference Title
REVIEW OF PROGRESS IN QUANTITATIVE NONDESTRUCTIVE EVALUATION

Keywords

acoustic microscopy, elastic stiffness, hypertension, pulmonary artery, tissue characterization, transversely isotropic

Citation

Waters, K. and Mukdadi, O. (2005), Ultrasonic Estimation of Mechanical Properties of Pulmonary Arterial Wall under Normoxic and Hypoxic Conditions, REVIEW OF PROGRESS IN QUANTITATIVE NONDESTRUCTIVE EVALUATION, Golden, CO, [online], https://doi.org/10.1063/1.1916853 (Accessed April 15, 2024)
Created April 9, 2005, Updated January 27, 2020