A comprehansive methodology has been developed for obtaining and using smoke toxicity data for fire hazard analysis. The methodology comprises: determination that the post-flashover fire is the propert focus of smoke inhalation deaths; criteria for a useful bench-scale toxic potency (LC50) measurement method; a method which meets these criteria, especially validation against real-scale fires; a computational procedure for correcting the results for the CO levels observed in real-scale post-flashover fires; procedures for reducing the usage of animals and broadening the applicability of data by interpreting gas measurement data using the N-Gas Model; and a procedure for identifying whether a product produces smoke within the ordinary range of toxic potency for post-flashover fires. The method is currently being developed for standardization by the National Fire Protection Association and the American Society for Testing and Materials.
Proceedings Title: U.S./Japan Government Cooperative Program on Natural Resources (UJNR)
Conference Dates: October 27-November 2, 1992
Conference Location: Tsukuba,
Conference Title: Fire Research and Safety. 12th Joint Panel Meeting
Pub Type: Conferences
fire safety, fire research, hazard analysis, fire hazard, toxicity, LC 50, animals, rats