Petersen, E.
, Marquis, B.
, Jaruga, P.
, , M.
and Nelson, B.
(2013),
Tools and Approaches for the Assessment of Nanomaterial Induced Oxidative DNA Damage, Nanotech 2013, Washington, DC, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=913562
(Accessed September 11, 2024)
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Tools and Approaches for the Assessment of Nanomaterial Induced Oxidative DNA Damage
Published
Author(s)
, Bryce Marquis, , ,
Abstract
Hyphenated mass spectrometry techniques have been employed as one of the primary analytical tools for investigating the effects of ionizing radiation, chemical/biological carcinogens, and oxygen derived free radicals on the induction and subsequent repair of oxidatively-induced DNA damage (DNA lesions) in living systems. The National Institute of Standards and Technology has established a comprehensive research program focused on identifying mechanisms of DNA damage caused by commercially relevant engineered nanoparticles (NPs) using high resolution mass spectrometry for the quantification of oxidatively-induced DNA damage. We present results from a recently published study on the genotoxicity of National Institute of Standards and Technology (NIST) standard reference material (SRM) gold nanoparticles using isotope dilution liquid chromatography /mass spectrometry analysis.Proceedings Title
Nanotech 2013
Conference Dates
May 12-16, 2013
Conference Location
Washington, DC
Pub Type
Conferences
Download Paper
Citation
Issues
If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.
Created May 13, 2013, Updated February 19, 2017