Three-dimensional Shape Metrology for Tissue Engineering

Published

April 21, 2012

Author(s)

Joy P. Dunkers, Antonio M. Possolo, Thomas V. Lafarge, Beatriz Pateiro-Lopez, Jeffrey Coles, Carl G. Simon Jr.

Abstract

The physical and chemical properties of a tissue scaffold influences cell response and therefore the success of the resulting tissue construct. Scaffold structure from nanometers to millimeters can direct cell behavior, from viability to proliferation to differentiation.We have developed three dimensional (3D) computational approaches to quantitatively describe scaffold geometry and capture the critical scaffold metrics that influence cell response. In this work, we present the computational infrastructure developed for the 3D calculation scaffold shape metrics and present these metrics for a scaffold with simple geometry.

Proceedings Title

Proceedings of the 2012 Society for Biomaterials Fall Symposium

Volume

1

Issue

1

Conference Dates

October 3-6, 2012

Conference Location

New Orleans, LA

Conference Title

Society for Biomaterials 2012 Fall Symposium

Pub Type

Conferences

Keywords

scaffold, structure, metrology, free form fabrication, polymer, connectivity, tortuosity

Citation

Dunkers, J. , Possolo, A. , Lafarge, T. , Pateiro-Lopez, B. , , J. and Simon, C. (2012), Three-dimensional Shape Metrology for Tissue Engineering, Proceedings of the 2012 Society for Biomaterials Fall Symposium, New Orleans, LA (Accessed October 15, 2025)