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Terahertz Spectroscopy of Biomolecules



David F. Plusquellic, Edwin J. Heilweil


Far-infrared (Terahertz or THz) spectroscopic investigations of condensed-phase biological and model organic species including substituted benzenes, amino acids, sugars, polypeptides, small proteins and DNA/RNA are reviewed. These studies reveal that for solid-state crystalline samples, a high degree of structural information can be extracted from THz spectra and that detailed internal vibrational motions and external molecular-host interactions are revealed. Generally, the THz spectra for high molecular weight polymers such as DNA/RNA or proteins or aqueous samples of any type exhibit broadband absorption but without identifying absorption features. Nevertheless, careful investigations have revealed new insight into the dynamics of these systems. Distinctly rich spectra for lower molecular weight systems (ca.
Terahertz Spectroscopy of Biomolecules
Publisher Info
Book CRC Press Book titled THz Specrtoscopy: Principles and Applications,


absorption spectra, biosystems and health, CHARMM, CPMD, DMo13, DNA and RNA, peptides, sugars, THz-TDS


Plusquellic, D. and Heilweil, E. (2007), Terahertz Spectroscopy of Biomolecules, Book CRC Press Book titled THz Specrtoscopy: Principles and Applications, , [online], (Accessed July 19, 2024)


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Created December 22, 2007, Updated February 17, 2017