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Structure and Dimensions of PAMAM/PEG Dendrimer-Star Polymers
Published
Author(s)
R C. Hedden, Barry J. Bauer
Abstract
Dendrimer-star polymers are prepared by grafting monofunctional poly(ethylene glycol) (PEG) chains of low polydispersity onto the terminal groups of poly(amidoamine) (PAMAM) dendrimers. A novel gel permeation chromatography technique is used to calculate the average number of PEG branches (arms) per star. The maximum number of PEG arms (of Mn = 5,000 g mol-1) ranges from about 30 arms for a Generation 3 dendrimer-star to about 750 arms for a Generation 10 dendrimer-star. Radii of gyration of the stars are measured in dilute solution in a good solvent (methanol-d4) by small-angle neutron scattering (SANS). The stars have measured radii of gyration of (5 to 14) nm. Dendrimer-stars are modeled as a shell of linear chains tethered to a spherical core. The core radius is taken to be the measured hydrodynamic radius of the dendrimer. The density distribution within the shell and the shell thickness are adopted from a model of Vagberg, Cogan, and Gast.The radii of gyration computed from the core-shell model are consistent with the measured values from SANS.
dendrimer, neutron scattering radius of gyration, polymer brush, star polymer
Citation
Hedden, R.
and Bauer, B.
(2003),
Structure and Dimensions of PAMAM/PEG Dendrimer-Star Polymers, Macromolecules, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852070
(Accessed December 1, 2023)