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Search Publications by: Subrata Mishra (Fed)

Displaying 1 - 2 of 2

Comprehensive solution NMR characterization of the direct thrombin inhibitor peptide bivalirudin and its process impurities by heteronuclear mapping at natural isotopic abundance.

July 29, 2026

Author(s)

Subrata Mishra, Anupreet Kaur, Sitaram Bhavaraju

Bivalirudin is a 20-residue synthetic peptide that functions as a bi-valent thrombin inhibitor by simultaneously engaging thrombin's active site and exosite I. Despite its widespread clinical use, comprehensive NMR-based characterization of bivalirudin and

From Obscurity to Prominence: IPMK's Expanding Role in Cellular Signaling, Physiology, and Disease

September 1, 2025

Author(s)

Subrata Mishra, Prasun Guha

Inositol polyphosphate multikinase (IPMK) is a versatile enzyme with dual inositol and lipid kinase activities, crucial for generating key signaling molecules like InsP5 (inositol pentaphosphate), InsP6 (inositol hexaphosphate), and PIP3 (phosphoinositide

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