Publications

Displaying 1 - 4 of 4

Rapid Analysis of Drugs: A Tool to Detect Drug Overdose Spikes, Build Trust Among People Using Drugs and Reduce Overdoses - Maryland, November 2021 - August 2022

April 28, 2023

Author(s)

Erin Russell, Edward Sisco, Allison Thomson, Jasmine Lopes, Dana Heilman, Margaret Rybak, Malik Burnett, Meghan Appley, Matthew Gladden

Maryland overdose deaths increased 16%, to a record high of 2,912 deaths during the 12-month period from July 2020 to June 2021. Illicitly manufactured fentanyl and/or fentanyl analogs* contributed to 84% of these overdose deaths.† Timely public health

Identification of the Veterinary Sedative Medetomidine in Combination with Opioids and Xylazine in Maryland

March 26, 2023

Author(s)

Edward Sisco, Meghan Appley

Public health, public safety, and forensic science personnel continue to face the emergence of new compounds into the drug market. While focus is often put on the detection of new analogs of known illicit drugs, monitoring the changes in cutting agents and

An Analytical Platform for Near Real-Time Drug Landscape Monitoring using Paraphernalia Residues

March 13, 2023

Author(s)

Meghan Appley, Liz Robinson, Allison Thomson, Erin Russell, Edward Sisco

Deaths attributed to drug overdoses are constantly on the rise, but drug trends are frequently changing and often differ across geographical regions. Current analytical techniques are limited in their abilities to rapidly identify drugs that would inform

Qualitative Analysis of Real Drug Evidence using DART-MS and the Inverted Library Search Algorithm

August 25, 2022

Author(s)

Edward Sisco, Meghan Appley, Stephen Tennyson, Arun Moorthy

Chromatographic-less mass spectrometry techniques like direct analysis in real time mass spectrometry (DART-MS) are steadily being employed as seized drug screening tools. However, these newer analytical platforms require new computational methods to best

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