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Search Publications by: Samuel Schaffter (Fed)

Displaying 1 - 2 of 2

Design approaches to expand the toolkit for building cotranscriptionally encoded RNA strand displacement circuits

May 3, 2023

Author(s)

Samuel Schaffter, Molly Wintenberg, Terence Murphy, Elizabeth Strychalski

Cotranscriptionally encoded RNA strand displacement (ctRSD) circuits are an emerging tool for programmable molecular computation, with potential applications spanning in vitro diagnostics to continuous computation inside living cells. In ctRSD circuits

Cotranscriptionally encoded RNA strand displacement circuits

March 23, 2022

Author(s)

Samuel Schaffter, Elizabeth Strychalski

Engineered molecular circuits that process information in biological systems could address emerging human health and biomanufacturing needs. However, such circuits can be difficult to rationally design and scale. DNA-based strand displacement reactions