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Search Publications by: Paul Patrone (Fed)

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Displaying 26 - 50 of 79

DYNAMIC MEASUREMENT OF NANOLITER PER MINUTE FLOW BY SCALED DOSAGE OF FLUORESCENT SOLUTIONS

October 3, 2020
Author(s)
Gregory A. Cooksey, Paul Patrone, James R. Hands, Stephen E. Meek, Anthony J. Kearsley
This work describes a new method for continuous measurement of flow in a microchannel from 1 nL/min to 1000 nL/min using an optofluidic device with waveguides that deliver and collect light from small regions of a microfluidic channel. By relating the

Measuring Microfluidic Flow Rates: Monotonicity, Convexity and Uncertainty

August 20, 2020
Author(s)
Paul Patrone, Qing Hai Li, Gregory A. Cooksey, Anthony J. Kearsley
A class of non-linear integro-differential equations characterizing microfluidic measurements is considered. Under reasonable conditions, these non-linear integro-differential equations admit solutions that are convex functions of an interesting flow-rate

Revealing thermodynamics of DNA origami folding via affine transformations

June 4, 2020
Author(s)
Jacob M. Majikes, Paul N. Patrone, Daniel R. Schiffels, Michael P. Zwolak, Anthony J. Kearsley, Samuel P. Forry, James A. Liddle
Structural DNA nanotechnology, as exemplified by DNA origami, has enabled the design and construction of molecularly precise objects for a myriad of applications. However, limitations in imaging, and other characterization approaches, make a quantitative

Best Practices for Quantification of Uncertainty and Sampling Quality in Molecular Simulations

October 27, 2018
Author(s)
Alan Grossfield, Paul Patrone, Daniel R. Roe, Andrew J. Schultz, Daniel Siderius, Daniel M. Zuckerman
The quantitative assessment of uncertainty and sampling quality is essential in molecular simulation. Many systems of interest are highly complex, often at the edge of current computational capabilities. Modelers must therefore analyze and communicate