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Search Publications by: Anthony J. Kearsley (Fed)

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Displaying 101 - 125 of 151

Numerical Optimization of Matrix-Assisted Laser Desorption/Ionization Time-of- Flight Mass Spectrometry: Application to Synthetic Polymer Molecular Mass Distribution Measurement

May 26, 2007
Author(s)
William E. Wallace, Charles M. Guttman, Kathleen M. Flynn, Anthony J. Kearsley
A novel approach is described for the selection of optimal instrument parameters that yield a mass spectrum which best replicates the molecular mass distribution of a synthetic polymer. The application of implicit filtering algorithms is shown to be a

Flow Control Through the Use of Topography

May 1, 2007
Author(s)
David Cotrell, Anthony J. Kearsley
In this work, optimal shaft shapes for flow in the annular space between a rotating shaft with axially-periodic radius and a fixed coaxial outer circular cylinder are investigated. Axisymmetric steady flows in this geometry are determined by solving the

Development of NIST SRM 2881, an Absolute Molecular Mass Distribution Polymer Standard

September 1, 2006
Author(s)
William E. Wallace, Charles M. Guttman, Kathleen M. Flynn, Anthony J. Kearsley
We present a strategy to create an absolute molecular mass distribution polymer Standard Reference Material. To create a standard our methods must be free of operator bias (intentional or unintentional). The steps include sample preparation, instrument

Recovering Circles and Spheres from Point Data

July 1, 2006
Author(s)
Christoph J. Witzgall, Geraldine Cheok, Anthony J. Kearsley
Methods for fitting circles and spheres to point sets are discussed. LADAR (LAser Detection And Ranging) scanners, in particular, are capable of generating "point clouds" containing the x, y, z coordinates of up to several millions of points reflecting the

Recovering Spheres from 3D Point Data

April 1, 2006
Author(s)
Christoph J. Witzgall, Geraldine Cheok, Anthony J. Kearsley
The National Institute of Standards and Technology is involved in developing standard protocols for the performance evaluation of 3D imaging systems, which include laser scanners and LADARs (LAser Detection and Ranging). A LADAR is an optical device that

Projections Onto Order Simplexes and Isotonic Regression

March 31, 2006
Author(s)
Anthony J. Kearsley
We begin this expository essay by reviewing with examples what a typical engineer already knows about statistics. We then consider a central question in engineering decision making, i.e., given a computer simulation of high-consequence systems, how do we

A Numerical Method for Mass Spectral Data Analysis

January 31, 2005
Author(s)
Anthony J. Kearsley, William E. Wallace, Javier Bernal, Charles M. Guttman
The new generation of mass spectrometers produces an astonishing amount of high-quality data in a brief period of time leading to inevitable data analysis bottlenecks. Automated data analysis algorithms are required for rapid and repeatable processing of

An Operator-Independent Approach to Mass Spectral Peak Identification and Integration

May 1, 2004
Author(s)
William E. Wallace, Anthony J. Kearsley, Charles M. Guttman
A mathematical algorithm is presented that accurately locates and calculates the area beneath mass spectral peaks using only reproducible mathematical operations and a NO user-selected sensitivity parameters. This represents a major refinement of last year