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Tsega Solomon, Frank Delaglio, John Giddens, John Marino, Yihua Bruce Yu, Marc Taraban, Robert Brinson
The clinical efficacy and safety of protein-based drugs such as monoclonal antibodies (mAbs) rely on the integrity of the protein higher order structure (HOS) during product development, manufacturing, storage, and patient administration. As mAb-based
Chuck Barber, Colleen E. Bryan Sallee, Carolyn Burdette, Shaun Kotoski, Melissa M. Phillips, Walter Brent Wilson, Laura Wood
In 2020, NIST launched CannaQAP to improve the comparability of the analytical measurements of cannabis and cannabis-derived products in forensic and cannabis (hemp and marijuana) testing laboratories. CannaQAP is an interlaboratory study mechanism that is
Susanna Mosleh, Jason Coder, Keith Forsyth, Mohamad Omar Al Kalaa, Christopher Scully
Objective: Respiratory motion (i.e., motion pattern and rate) can provide valuable information in many medical situations. This information may help diagnose different health disorders and diseases. Wi-Fi-based respiratory monitoring schemes utilizing
Johanna Camara, Jeanita Pritchett, Yasmine Daniels, Mary Bedner, Michael Nelson, Mark Lowenthal, Zia Fazili, Christine Pfeiffer, Karen W. Phinney, Katherine E. Sharpless, Lane C. Sander, Katrice Lippa, James H. Yen, Adam Kuszak, Stephen Wise
The US National Institute of Standards and Technology (NIST) developed a Standard Reference Material® (SRM®) 3949 Folate Vitamers in Frozen Human Serum to replace SRM 1955 Homocysteine and Folate in Human Serum. The presence of increased endogenous levels
Sarah Commodore, Steven J. Christopher, Bethany Wolf, Erik Svendsen
Abstract Background: Exposure to particulate air pollution is one of the greatest environmental risk factors for adverse human health outcomes. However, the constituents responsible for such adverse health effects have not been fully studied. Current
Stephanie Servetas, Kirsten Parratt, NIchole Brinkman, Orin Shanks, Ted Smith, Philip Mattson, Nancy Lin
The COVID-19 pandemic highlighted a wide range of public health system challenges for infectious disease surveillance. The discovery that the SARS-CoV-2 virus was shed in feces and can be characterized using PCR-based testing of sewage samples offers new
Kathy Burek-Huntington, Kim Shelden, Kim Goetz, Barbara Mahoney, Dan Vos, Jessica Reiner, Jennifer Hoguet, Greg O'Corry-Crowe
Throughout the State of Alaska, ranging from the eastern Beaufort Sea to Bristol Bay, and within the boundaries of Cook Inlet, belugas are an important subsistence resource for Native communities. Cook Inlet belugas (CIBs, Delphinapterus leucas) are
Mary Clare McCorry, Marcie Black, Chrysanthi Williams, Greta Babakhanova, Sumona Sarkar, Nathan Swami, Katherine A. Mirica, Sarah Boermeester, Abbie Underhill
The use of engineered cells, tissues, and organs has the opportunity to change the way injuries and diseases are treated. Commercialization of these groundbreaking technologies has been limited in part by the complex and costly nature of their manufacture
Erich Jarvis, Giulio Formenti, Jennifer McDaniel, Nathanael David Olson, Justin Wagner, Justin Zook, Kerstin Howe, Karen Miga
The current human reference genome, GRCh38, represents over 20 years of effort to generate a high-quality assembly, which has benefitted society. However, it still has many gaps and errors, and does not represent a biological genome as it is a blend of
We establish here a set of cytocentric principles to improve use of cells for regenerative medicine (RM) applications. The five cytocentric principles are cells need 1) full-time protection from contamination, 2) physiologic simulation, 3) proper
Artificial intelligence (AI) systems are increasingly seen in many public facing applications such as self-driving land vehicles, autonomous aircraft, medical systems and financial systems. AI systems should equal or surpass human performance, but given
Nancy Lin, Scott Jackson, Stephanie Servetas, Kirsten Parratt, Joy Dunkers, Tara Eskandari, Sheng Lin-Gibson
On September 17, 2020, NIST hosted a virtual workshop to launch the Rapid Microbial Testing Methods (RMTM) Consortium. The RMTM Consortium aims to address the need for measurements and standards to increase confidence in the use of rapid testing for
Standard Reference Material (SRM) 915c Calcium Carbonate is certified as a chemical substance of known purity. It is intended for use in the calibration and standardization of procedures for calcium (Ca) determinations employed in clinical analysis and for
Min Chen, Hamid Gharavi, LIN WANG, VICTOR.C.M LEUNG, Zhongchun Liu, Iztok Humar
Case studies on AI-aided emotion care and mental disorder patient monitoring can contribute to providing knowledge and research direction for scholars. Well-studied and persuasive case studies help professionals and the public to fully accept changes and