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Testing standards are more fundamental from a metrological perspective and less controversial from an industrial perspective than product standards, representing a path of less resistance towards the standardization and commercialization of lab on a chip
Konrad Rykaczewski, William A. Osborn, Jeff Chinn, Marlon L. Walker, John H. Scott, Wanda Jones, Chonglei Hao, Shuhuai Yao, Zuankai Wang
Surfaces which evince superhydrophobic properties during water condensation have a potential to dramatically enhance energy efficiency in power generation and desalination systems. Although various such surfaces have been reported, their development has
Conni Hanke, Petra S. Dittrich, Darwin Reyes-Hernandez
We present a new system for cell capturing on permeable polyester (PET) membranes using dielectrophoretic forces. For the first time gold microelectrodes were fabricated on PET membranes using conventional photolithographic techniques. Their
We developed a computational model and theoretical framework to investigate the geometrical optimization of particle-surface interactions in a herringbone micromixer. The enhancement of biomolecule- and particle-surface interactions in microfluidic devices
The tremendous growth of fluorescence applications in the life and material sciences has proceeded largely without sufficient concern for the reliability and uncertainties related to the characterization and performance validation of fluorescence
John J. Curry, E. G. Estupinan, W. P. Lapatovich, Albert Henins, S. D. Shastri
The total vapor-phase densities of Dy in equilibrium with a DyI$_3$/InI condensate and Tm in equilibrium with a TmI$_3$/TlI condensate have been measured for temperatures between 900 K and 1400 K. The measurements show strong enhancements in rare-earth
Immunomagnetic isolation and magnetophoresis in microfluidics have emerged as viable techniques for the separation, fractionation, and enrichment of rare cells. Here, we present the development and characterization of a microfluidic system that
Peter J. Lowell, Galen C. O'Neil, Jason M. Underwood, Joel N. Ullom
Normal metal - Insulator - Superconductor (NIS) tunnel junctions can be used to selectively remove the hottest elec- trons in the normal metal, thereby causing it to cool. NIS tunnel junctions have already been used to cool lithograph- ically integrated
Francisco J. Atencia, Gregory A. Cooksey, Laurie E. Locascio
This manuscript describes a new method to generate purely diffusive chemical gradients that can be modified in time. The device is simple in its design and easy to use, which makes it amenable to study biological processes that involve static or dynamic
Esther Baumann, Fabrizio R. Giorgetta, William C. Swann, Alexander M. Zolot, Ian R. Coddington, Nathan R. Newbury
We demonstrate a high-accuracy dual-comb spectrometer centered at 3.4 υm. The amplitude and phase spectra of the P,, Q, and partial R branches of the methane Ņ3 band are measured at 25 to 100 MHz point spacing with resolution under 10 kHz and a signal-to
The influence of ambient pressure below atmospheric and heating rate on bubble dynamics associated with rapid evaporation in highly superheated water is investigated in this work. The average surface temperature of thin platinum strips immersed in water is
The computations reported in this paper were done in conjunction with an experimental study involving single pulse shock tube measurements of the thermal decomposition of three chloroalkanes, and that work is reported in an accompanying preceding paper
Ryan J. Lewis, Mu Hong Lin, Yunda Wang, Jill Cooper, Peter E. Bradley, Ray Radebaugh, Marcia L. Huber, Yung-Cheng Lee
Joule-Thompson (J-T) based micro cryogenic coolers (MCCs) are attractive because they can provide the cryogenic temperatures needed for small electronic devices while having a low cost and small volumetric footprint. A compressor is a major part of a
Nathan D. Orloff, Jaclyn R. Dennis, Marco Cecchini, Ethan Schonbrun, Eduard Rocas, Yu Y. Wang, David R. Novotny, Raymond W. Simmonds, John M. Moreland, Ichiro Takeuchi, James C. Booth
We present a 91 MHz surface acoustic wave resonator with integrated microfluidics that includes a flow focus, an expansion region, and a binning region. We demonstrate the ability to change the position of the acoustic nodes by varying the electronics
Yunda Wang, Ryan J. Lewis, Mu Hong Lin, Yiwei Yan, Ray Radebaugh, Peter E. Bradley, Yung-Cheng Lee
A heat exchanger (HX) plays an important role in many cryogenic systems. This paper demonstrates a fully integrated fabrication process to make a novel monolithic polyimide micro heat exchanger. The structure of this heat exchanger consists of two parallel
Konrad Rykaczewski, John H. Scott, Sukumar Rajauria, W R. Ashurst, Jeff Chinn, Amy Chinn, Wanda Jones
We report formation of nano-to-microscale satellite droplets in the geometrical shadow of high contact angle primary drops during dropwise water condensation on a nanostructured superhydrophobic surface. The primary drops contribute to the heat transfer
Joseph T. Hodges, David A. Long, Daniel K. Havey, S. S. Yu, M Okumura, Charles E. Miller
Frequency-stabilized cavity ring-down spectroscopy (FS-CRDS) was employed to measure over 100 transitions in the R-branch of the b1Σg+←X3Σg-(0,0) band for the rare O2 isotopologues. The use of 17O- and 18O-enriched mixtures allowed for line positions to be
Alyssa Henry, David J. Ross, Elizabeth Strychalski
Gradient elution moving boundary electrophoresis (GEMBE) is a robust continuous injection separation technique that uses electrophoresis to drive electrically charged analytes into a capillary or microfluidic channel for detection, while opposing
Joseph T. Hodges, A. Cygan, Piotr Maslowski, Katarzyna E. Bielska, S. Wojtewicz, J. Domyslawska, Hisashi Abe, R.S. Trawinski, R. Ciurylo
We describe a high sensitivity and high spectral resolution laser absorption spectrometer based upon the frequency-stabilized cavity ring-down spectroscopy (FS-CRDS) technique. We used the Pound-Drever-Hall (PDH) method to lock the probe laser to the high
The proposal by NASA to use high temperature superconducting (HTS) generators and motors on future (2035) aircraft for turboelectric propulsion imposes difficult requirements for cryocoolers. Net refrigeration powers of about 5 kW to 10 kW at 50 K to 65 K
Peter E. Bradley, Ray Radebaugh, Ryan J. Lewis, Mu Hong Lin, Yung-Cheng Lee
Previously we demonstrated cryogenic cooling in a Joule-Thomson microcryocooler (MCC) with mixed refrigerants operating at pressure ratios of 16:1 that achieved stable temperatures of 140 K with transient temperatures down to 76 K with precooling of the
Gregory A. Cooksey, John T. Elliott, Anne L. Plant
Numerous opportunities exist to apply microfluidic technology to high-throughput and high-content cell-based assays. However, maximizing the value of these assays for drug discovery, screening or toxicity evaluation, for example, will require validation of
Ryan J. Lewis, Yunda Wang, Jill Cooper, Mu Hong Lin, Victor M. Bright, Yung-Cheng Lee, Peter E. Bradley, Ray Radebaugh, Marcia L. Huber
Joule-Thomson micro cryogenic coolers (MCCs) are a preferred approach for small and low power cryocoolers. With the same heat lift, MCC's power input can be only 1/10 of a thermoelectric cooler's input, and MCC's size can be only 1/10 of a Stirling cooler
We derive path-integral expressions for the second and third virial coefficients of monatomic quantum gases. Unlike previous work that considered only Boltzmann statistics, we include exchange effects (Bose-Einstein or Fermi-Dirac statistics). We use state