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Reversed-Flow Chromatographic Determination of Binary Diffusion Coefficients



William S. McGivern, Jeffrey A. Manion


A reversed-flow chromatographic apparatus for the measurement of binary diffusion coefficients is described. Hydrocarbons are detected using flame ionization detection, and inert species can be detected by thermal conductivity. We have measured the binary diffusion coefficients for several systems at temperatures from (300­723) K. Characterization of the new apparatus was accomplished by comparing measured binary diffusion coefficients of dilute argon in helium to literature values. Further diffusion coefficients for dilute helium in argon as well as nitrogen in helium were measured using a thermal conductivity detector. Dilute methane in helium diffusion coefficients were measured using flame ionization detection and found to be in excellent agreement with literature values. Simulations of the diffusion show specific dependences on diffusion time and injection volume that must be considered to ensure the measurement of accurate diffusion coefficients.
Journal of Chromatography A


diffusion, chromatography, combustion, hydrocarbons


McGivern, W. and Manion, J. (2011), Reversed-Flow Chromatographic Determination of Binary Diffusion Coefficients, Journal of Chromatography A (Accessed May 18, 2024)


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Created September 19, 2011, Updated February 19, 2017